“…This common characteristic of lability among fish venoms is clinically important, as demonstrated by the effective use of heat in relieving symptoms of envenomation. While there is debate as to whether heat actually breaks down the venom or relieves symptoms by other mechanisms (Fenner, 2000), immersing an envenomed body part in hot water has been shown to be effective in alleviating the symptoms of envenomation by almost all species of venomous fish (Chan et al, 1996;Fenner, 2000;Halstead, 1967;Kasdan et al, 1987;Kizer, 1984;Kizer et al, 1985;Patel and Wells, 1993;Rifkin and Williamson, 1996;Russell, 1996;Sutherland and Tibballs, 2001;Trestrail and Al-Mahasneh, 1989;Wasserman and Johnston, 1979).…”