Lipid and lipoprotein profiles and prevalence of dyslipidemia in Mexican adolescents

Posadas-Sánchez, Rosalinda; Posadas‐Romero, Carlos; Zamora-González, José; Mendoza-Pérez, Enrique; Cardoso-Saldaña, Guillermo; Yamamoto-Kimura, Liria

doi:10.1016/j.metabol.2007.07.009

Cited by 39 publications

(36 citation statements)

References 47 publications

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“…In the previous studies, low HDL-C levels in overweight and obese adolescents were reported and this was also confirmed in our study [14,26]. In the present study, only HDL-C levels were significantly different between obese subjects with and without FL in Doppler US group.…”

Section: Discussionsupporting

confidence: 91%

Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents

et al. 2010

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(1) to evaluate the frequency of asymptomatic fatty liver disease (FLD) using both Doppler and B-mode ultrasound (US) in overweight and obese adolescents; (2) to compare metabolic findings of fatty liver (FL) assessed by two methods; and (3) to evaluate metabolic predictors of FL shown by these methods. Fifty-nine overweight and obese adolescents aged between 9.0 and 17.0 years and 41 non-obese healthy adolescents were included in this study. B-mode and right hepatic vein Doppler ultrasonography (US) were performed and anthropometric indices, lipid profiles, and adiponectin levels were evaluated in all adolescents. HDL-C levels were significantly lower in patients with FL detected by Doppler US compared to patients without FL (p < 0.05). HDL-C levels were inversely correlated with presence of FL assessed by two methods (r = -0.285, p = 0.004; r = -0.328, p = 0.001, respectively) and adiponectin levels were correlated with presence of FL only detected by B-mode US (r = -0.263, p = 0.008). Adiponectin levels were significantly lower in patients with FL than those without FL assessed by B-Mode US (p = 0.049). Multiple regression analysis revealed that HDL-C levels was the most important predictor of FL assessed by Doppler US (p = 0.027), while body mass index was the determinant of FL assessed by two methods (p < 0.001) in asymptomatic overweight and obese adolescents. It was found that FLD, identified by both B-mode and Doppler US, is seen frequently in asymptomatic overweight and obese adolescents. Elevated BMI is associated with increased risk of FL assessed by two ultrasonographic methods. When using Doppler US, low HDL-C levels can be used as a good predictor for presence of FLD in overweight and obese adolescents.

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Section: Discussionsupporting

confidence: 91%

Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents

et al. 2010

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“…This result is in accordance with findings in Turkish, Bangalore, Mexican, and Brazilian study. 26,27,31,32 In contrast, in the study by Dholapuria et al, all the lipid variables except HDL-C were marginally higher in boys than girls. 25 These inconsistent results may be due to genetic variations and different dietary habits in Turkey, Mexico, Bangalore, Brazil, Bikaner, and Barabanki.…”

Section: Discussionmentioning

confidence: 85%

Lipid profile in school children: study from a District of Uttar Pradesh, India

Bansal

Rathoria

Gupta

et al. 2017

Int J Contemp Pediatr

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Background:Lipid imbalance when diagnosed in childhood, can forecast the development of atherosclerosis in adulthood and its complications. Therefore, early detection of dyslipidemia should begin in childhood and it should lead to long-term prevention of atherosclerosis by controlling the risk factors. The Objectives of the study were to study lipid profile of children in the age group of 10-19 years and the prevalence of dyslipidemia among them.Methods: This is a cross-sectional study, which was conducted in 300 children aged 10 to 19 years, of either sex, from schools of Barabanki. After getting consent from school authorities, children and their parents, a detailed history was taken with a pre-designed pro forma and fasting blood samples were analyzed for lipid profile.Results:Mean total cholesterol (TC) for boys and girls were 161.06±33.14 mg/dl and 164.68±33.53 mg/dl, LDL-C 99.35±27.41 mg/dl and 101.71±26.44 mg/dl, HDL-C 42.76±5.78 mg/dl and 43.93±5.68 mg/dl, VLDL-C 18.94±4.47 mg/dl and 19.04±4.97 mg/dl and triglycerides (TG) 94.69±22.34 mg/dl and 95.20±24.83 mg/dl respectively. Serum TC, TG, LDL-C, VLDL-C and HDL-C levels were higher in girls than in boys for all age groups. 26.55% boys and 25.20% girls had TC levels above 190 mg/dl. The overall results revealed that 26.0% of children had hypercholesterolemia.Conclusions:The study presents age- and sex-related findings about the dynamics of changes in serum lipid levels in children. Significant number of children had hypercholesterolemia.

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“…Likewise, when evaluating clinical-metabolic alterations in obese and non obese adolescents grouped according to gender, color, age, sexual maturation stage and schooling, lower HDL levels and superior triglycerides levels among obese adolescents were observed [24].…”

Section: Discussionmentioning

confidence: 97%

“…However, some studies did not identify differences in the lipid profile between genders [6] [20] [23]. Excess weight is an important risk factor for the development of cardiovascular alterations, predisposing individuals to the increase in total cholesterol, LDL, and triglycerides serum levels and to HDL reduction [24].…”

Section: Discussionmentioning

confidence: 99%

Dyslipidemias and Related Factors in Brazilian Adolescents from Rural and Urban Areas

Silva¹,

Franceschini²,

Novaes³

et al. 2014

Health

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This study aimed to evaluate the prevalence of dyslipidemias and related factors, in Brazilian adolescents from rural and urban areas. This is a cross-sectional study with 182 adolescents aged 10 to 13 years, students, residing in the rural and urban area of Brazil; grouped according to age, gender and socioeconomic class. Sexual maturation, physical activity, blood pressure, nutritional status and body composition were evaluated. Total cholesterol, LDL, HDL and serum triglycerides were dosed. The food frequency questionnaire was applied, quantifying energy, carbohydrates, proteins, lipids, full fat and fibers. Bivariate and multiple analyses were carried out, by logistic regression. It was verified that 84.6% (n = 154) adolescents presented some lipid profile alteration. There was no difference in the lipid profile between adolescents for residence place. However, as for gender, it was noticed that girls presented higher levels of total cholesterol and HDL (p < 0.05). In addition, adolescents with excess weight and body fat showed lower HDL and higher triglycerides values compared with eutrophic and with those with appropriate body fat percentage (p < 0.05). In the multiple analyses, it was observed that gender and signs of sexual maturation were associated with total cholesterol; fiber intake remained associated with HDL and signs of sexual maturation with LDL (p < 0.05). For triglycerides the related factors were gender, nutritional status and protein intake (p < 0.05). The elevated prevalence of dyslipidemias found between adolescents from rural and urban areas reinforces the importance of monitoring these alterations and information as for the related risk factors, with programs for correction of changeable factors.

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Lipid and lipoprotein profiles and prevalence of dyslipidemia in Mexican adolescents

Cited by 39 publications

References 47 publications

Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents

Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents

Lipid profile in school children: study from a District of Uttar Pradesh, India

Dyslipidemias and Related Factors in Brazilian Adolescents from Rural and Urban Areas

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