Lipid-Lowering Effects of Dietary Fiber.

Abstract

Soluble dietary fibers have been shown to reduce total plasma cholesterol and LDL-cholesterol, the two important risk factors for coronary heart disease. Multiple mechanisms appear to be involved in the hypocholesterolemic response, and data indicate that the profile of operating mechanisms may vary considerably among different dietary fiber sources. The mechanisms which have been suggested include binding of bile acids and interference with their enterohepatic circulation, interference with micelle formation, and reduced hepatic cholesterol synthesis. An examination of hypocholesterolemic action of dietary pectin indicates that this effect is due to a shift of cholesterol from plasma to the hepatic pools.

Preparation, structure characterization and functional properties of pea dregs resistant dextrin

“…Resistant dextrin reduces the secretion of digestive tract hormones that regulate the activity of digestive enzymes in the intestine to alter and maintain the balance of the metabolic activity of the body, which promotes human health (Xie et al, 2017). It has the physiological functions of regulating blood sugar (Shigeru et al, 1999;Aliasgharzadeh et al, 2015) and fat metabolism (Basu and Ooraikul, 2010;Dong et al, 2015), improving the composition of human intestinal colonies (Le et al, 2003;Barczynska et al, 2010;Lanubile et al, 2012), and being a laxative (Emilien et al, 2018;Pérez-Calahorra et al, 2020). Also, as a major water-soluble dietary fiber with good processing characteristics, it can be widely used in dairy products, baby food, pasta products, meat products, and other fields and has a broad application prospect.…”

Water-Soluble Viscous Substance of Jew's Mellow Leaves Lowers Serum and Liver Cholesterol Concentrations and Increases Fecal Steroid Excretion in Rats Fed a High Cholesterol Diet.

“…Water-soluble viscous dietary fibers are generally known to suppress the elevation of serum and liver TC in humans and animals alike (2-7). Although the mechanism of SDF to decrease cholesterol in rats fed a high cholesterol diet has not been clarified exactly, several factors are considered to be involved in such a mechanism (6,7,17). One of the most convincing theories is that cholesterol turnover is accelerated concomitantly with increased excretion of cholesterol and bile acids because absorption of exogenous cholesterol and fat is decreased and enterohepatic circulation of bile acids is suppressed due to inhibited formation of bile acid micelles in the upper part of the digestive tract (6, 7).…”

Genotype X Environment Interactions and Its Impact on Use of Medicinal Plants

“…Basu's research addressed these complex issues and provided critical evaluations of the validity of their clinical efficacy claims, and described an approach to a randomized, double-blind placebo-controlled clinical trial, which were designed taking into account the complexities that are involved in NHPs. The plants (and their products) that he investigated include germinated wheat [61]; rhubarb (Rheum rhaponticum L.) [62][63][64][65][66][67][68][69]; Echinacea (Echinacea purpurea L. Moench) [67,[70][71][72][73]; North American ginseng (Panax quinque folium L.) [61,74,75] and fenugreek (T. foenumgraecum L.) [33,34,36,37]. The lead authors association with Dr Basu's research started because of the common interest in fenugreek.…”