Lipid Management and the Elderly

Davidson, Michael; Kurlandsky, Sara; Kleinpell, Ruth M.; Maki, Kevin C.

doi:10.1111/j.1520-037x.2003.00557.x

Cited by 8 publications

(4 citation statements)

References 56 publications

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“…Serum lipid levels correlate to illnesses such as cardiovascular diseases and diabetes. 122 An investigation into the effectiveness of Baduanjin on blood lipid and antioxidant levels 70,80 indicated decreases in triglyceride, total cholesterol, malonyldialdehyde, low-density lipoprotein, whole blood viscosity, low shear blood viscosity and plasma viscosity, in contrast to increases in high-density lipoprotein, superoxide dismutase and glutathione peroxidase. Thus, these are able to ameliorate problems in the respiratory system.…”

Section: Metabolic Syndromementioning

confidence: 99%

The traditional Chinese Baduanjin exercise for the enhancements in health of older adults: a narrative review

Cheng

2018

Geriatr Care

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Health debilitation negatively impacts the physical and psychiatric states of ageing persons, consequently increasing individual, familial, and social burdens. Physical exercise is an effective measure to cope with this problem, and Baduanjin, a traditional Chinese exercise, is one of the choices. This narrative review analyses 58 clinical studies, which indicate the efficacy of Baduanjin for the health of old adults, including in physiological refinement, bone diseases, cardiovascular and cardiopulmonary illnesses, metabolic disorders, digestive sicknesses, cognitive impairment, and mental disorders. The results not only reveal the rehabilitative and preventive functions of Baduanjin, but also suggest health promotion through this physical activity for the ageing population. It also proposes improvements in methodological design and practical implications for the well being of seniors and successful ageing.

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Section: Metabolic Syndromementioning

confidence: 99%

The traditional Chinese Baduanjin exercise for the enhancements in health of older adults: a narrative review

Cheng

2018

Geriatr Care

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“…However, studies in the field of geriatrics, still at an early stage, are uncertain as to the predictive value of risk factors (RF) for CVD in the elderly, particularly in those older than 75 years. Based on this, some authors are currently studying the relationship between the process of atherosclerosis in the elderly and a number of RF (Kannel 1996; Howard et al 1997; Williams et al 2002; Davidson et al 2003). Aging, high blood pressure (BP), dyslipidemia, and obesity are among the RF that may lead to endothelial dysfunction and, therefore, to vascular changes.…”

Section: Introductionmentioning

confidence: 99%

Study of the intima-media thickening in carotid arteries of healthy elderly with high blood pressure and elderly with high blood pressure and dyslipidemia

Freitas

Brandão²,

Pozzan³

et al. 2008

CIA

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ObjectiveThe objective of this study was to assess the mean intima-media thickening of carotid arteries of elderly subjects, and its relationship with age, anthropometric measurements, high systolic blood pressure and dyslipidemia.MethodsIn this investigation, 129 subjects were enrolled between 1995 and 1998, age ranging from 29 to 94 years. They were assigned to one of 4 groups, including 2 control groups (group I, of healthy younger subjects; group II of healthy elderly subjects). Groups III and IV included those who presented with isolated systolic hypertension (ISH), and ISH and dyslipidemia, respectively. All subjects were submitted to a medical interview, lab tests with measurement of cholesterol levels, electrocardiogram, and carotid ultrasound. The ultrasound included measurement of the intima-media thickening (IMT) of the carotid arteries, the right carotid artery (RCA) and left carotid artery (LCA), and assessment of the presence of plaques. Blood fat and glucose were measured by a standard method. The results were compared among the groups through statistical tests. The tests employed were: Chi-Square, Pearson’s and Likelihood Ratio, Student’s t, Mann-Whitney; ANOVA followed by Tukey’s test, Kruskal-Wallis nonparametric test, and test for multiple comparisons and Odds Ratio determination (OR).ResultsIn this investigation, a positive association was observed between aging and IMT. In relation to systolic hypertension, a significant association was observed with IMT (IMT-RCA p = 0.0034; IMT-LCA p = 0.0196; IMT-RLCA p = 0.0299), and with the presence of plaques (PlaqueR p = 0.0110; PlaqueL p = 0.0294; PlaqueRL p = 0.0040).ConclusionThis investigation evidenced the important role of aging in IMT, and of systolic hypertension in the IMT and presence of plaque. However, further studies are needed for a better understanding of the actual role of risk factors in aging.

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“…21,25,28 -36 In addition, recent research offers compelling evidence that chronic psychological stress and negative affective states contribute significantly to the pathogenesis and progression of insulin resistance, [37][38][39][40][41] glucose intolerance, 38 hypertension, [42][43][44][45][46] dyslipidemia, 38,41,47 and other IRS-related conditions 28,37,48 -55 and ultimately, increase risk for CVD morbidity and mortality. 28,32,43,44,46,52,56 -60 Not only can IRS-related conditions be exacerbated by lifestyle variables, such as smoking, lack of exercise, and poor diet, but these conditions can interact with one another in a destructive manner, 61 likely accounting for their synergistic effect on CVD risk. 9,62 Thus, a vicious cycle is initiated, which, as time goes on, becomes increasingly difficult to treat, highlighting the importance of early intervention.…”

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confidence: 99%

Risk Indices Associated with the Insulin Resistance Syndrome, Cardiovascular Disease, and Possible Protection with Yoga: A Systematic Review

Innes

Bourguignon²,

Taylor³

2005

The Journal of the American Board of Family Medicine

323

261

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Objective: To conduct a systematic review of published literature regarding the effects of yoga, a promising mind-body therapy, on specific anthropometric and physiologic indices of cardiovascular disease (CVD) risk and on related clinical endpoints.Methods: We performed a literature search using 4 computerized English and Indian scientific databases. The search was restricted to original studies (1970 to 2004) evaluating the effects of yoga on CVD or indices of CVD risk associated with the insulin resistance syndrome (IRS). Randomized controlled trials (RCTs), nonrandomized controlled trials, uncontrolled (pre and post) clinical trials, and cross-sectional (observational) studies were included if they met specific criteria. Data were extracted regarding study design, setting, population size and characteristics, intervention type and duration, comparison group or condition, outcome assessment, data analysis and presentation, follow-up, and key results, and the quality of each study was evaluated according to specific predetermined criteria.Results : ing number of developing countries. [5][6][7] Leading to premature morbidity and mortality, and to preventable losses of employment, earnings, and quality of life, CVD is clearly of pressing clinical and economic significance, underscoring the need for effective primary prevention efforts that target common, modifiable risk factors. Prominent among these are the physiologic and anthropometric risk factors associated with the insulin resistance syndrome (IRS), and the neuroendocrine and psychosocial alterations that may both predispose to and result from these IRS-related abnormalities. The IRS, also referred to as syndrome X or the metabolic syndrome, is a cluster of metabolic and hemodynamic abnormalities that both collectively and independently predict the development of atherosclerosis and CVD. 4,8 -11 Core features of the IRS are insulin resistance, glucose intolerance, atherogenic dyslipidemia, high blood pressure, and

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Lipid Management and the Elderly

Cited by 8 publications

References 56 publications

The traditional Chinese Baduanjin exercise for the enhancements in health of older adults: a narrative review

The traditional Chinese Baduanjin exercise for the enhancements in health of older adults: a narrative review

Study of the intima-media thickening in carotid arteries of healthy elderly with high blood pressure and elderly with high blood pressure and dyslipidemia

Risk Indices Associated with the Insulin Resistance Syndrome, Cardiovascular Disease, and Possible Protection with Yoga: A Systematic Review

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