Lipid metabolism and plasma metabolomics of juvenile largemouth bass Micropterus salmoides were affected by dietary oxidized fish oil

Xie, Shiwei; Yin, Peng; Liu, Tian; Liu, Yongjian; Niu, Jin

doi:10.1016/j.aquaculture.2020.735158

Cited by 69 publications

(22 citation statements)

References 50 publications

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“…Gene expression was conducted to further evaluate the effect of dietary lipid levels on lipid metabolism of Japanese seabass. Apoa1 is necessary for the transport of lipid (Xie et al, 2020), the significant higher apoa1 expression in fish fed L178.6 indicated the lipid transportation was more active in fish fed a high‐fat diet than those fed a low fat diet. Atgl , PPARα and cpt ‐ 1 are three genes related to lipolysis (Wei et al, 2017), high dietary lipid enhanced the lipolysis of fish in this study.…”

Section: Discussionmentioning

confidence: 99%

Dietary lipid levels affected growth performance, lipid accumulation, inflammatory response and apoptosis of japanese seabass (lateolabraxjaponicus)

Xie

Lin

et al. 2021

Aquacult. Nutr.

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An eight weeks feeding trial was conducted to investigate the effects of dietary lipid levels on growth performance, lipid metabolism and immune response of Japanese seabass (Lateolabrax japonicus). Five diets were formulated with gradient dietary lipid levels (79.6, 104.4, 129.1, 154.9 and 178.6 g kg−1). Results revealed that growth and feed utilization of fish were significantly lower in group L178.6 than other groups (p < 0.05). Lipid accumulation in whole body, muscle and intraperitoneal were increased with increasing dietary lipid levels. The mRNA levels of adipose triglyceride lipase, carnitine palmitoyl transferase 1, acetyl CoA carboxylase, cholesterol 7 alpha‐hydroxylase and retinoid X receptor in liver were also increased with increasing dietary lipid levels (p < 0.05). The mRNA levels of apolipoprotein A1 and peroxisome proliferator activating receptor α were higher in fish fed L178.6 than those fed other diets. Oxidative stress in plasma and liver were induced when dietary lipid exceed 154.9 g kg−1. L154.9 and L178.6 significantly increased the inflammatory related gene expression of fish. These results suggested that high‐fat diet impaired the growth performance and induced lipid accumulation, inflammation and apoptosis of Japanese seabass. The suitable dietary lipid level of Japanese seabass may not exceed 129.1 g kg−1.

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Section: Discussionmentioning

confidence: 99%

Dietary lipid levels affected growth performance, lipid accumulation, inflammatory response and apoptosis of japanese seabass (lateolabraxjaponicus)

Xie

Lin

et al. 2021

Aquacult. Nutr.

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“…The lower expression of PPARα in the HFA2 group compared to the HF group indicated the lower lipid content in the liver, which was positively correlated with the HSI results. HMGCR is the rate-limiting enzyme for cholesterol synthesis of largemouth bass [ 37 ], the low HMGCR expression may associate with the high hepatic TC content. In this study, dietary astaxanthin supplementation enhanced the hepatic mRNA expression of HMGCR , similar results were found in mice [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Dietary Supplementation of Astaxanthin Improved the Growth Performance, Antioxidant Ability and Immune Response of Juvenile Largemouth Bass (Micropterus salmoides) Fed High-Fat Diet

et al. 2020

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High-fat diet (HFD) usually induces oxidative stress and astaxanthin is regarded as an excellent anti-oxidant. An 8-week feeding trial was conducted to investigate the effects of dietary astaxanthin supplementation on growth performance, lipid metabolism, antioxidant ability, and immune response of juvenile largemouth bass (Micropterus salmoides) fed HFD. Four diets were formulated: the control diet (10.87% lipid, C), high-fat diet (18.08% lipid, HF), and HF diet supplemented with 75 and 150 mg kg−1 astaxanthin (HFA1 and HFA2, respectively). Dietary supplementation of astaxanthin improved the growth of fish fed HFD, also decreased hepatosomatic index and intraperitoneal fat ratio of fish fed HFD, while having no effect on body fat. Malondialdehyde content and superoxide dismutase activity were increased in fish fed HFD, astaxanthin supplementation in HFD decreased the oxidative stress of fish. The supplementation of astaxanthin in HFD also reduced the mRNA levels of Caspase 3, Caspase 9, BAD, and IL15. These results suggested that dietary astaxanthin supplementation in HFD improved the growth performance, antioxidant ability and immune response of largemouth bass.

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“…The relative expression levels of CYP7A1, CYP8B1, FXR, IL1β, NF-κβ1, OSTα, NTCP and PPARα were quantified. Published primers were used to quantify the expression levels of PPARα, IL1β (Yu et al, 2019), CYP7A1, CYP8B1 (Yu et al, 2018) and FXR (Xie et al, 2020).…”

Section: Quantitative Real-time Pcrmentioning

confidence: 99%

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

Cai

Ren

et al. 2021

Aquaculture Research

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Dietary fibre (DF) is defined as 'non-digestible carbohydrates plus lignin' and includes non-starch polysaccharides (NSPs), hydrocolloids, resistant starch, resistant oligosaccharides and lignin associated with DF polysaccharides (Stephen et al., 2017). DF is not digested and absorbed by monogastric animals (Sinha et al., 2011), but can be fermented by intestinal microbiota (Miao et al., 2018).Therefore, it can regulate the structure of intestinal microbiota and improve intestinal health (Lin et al., 2020). In addition, DF has bile acid (BA) binding capacity Naumann et al., 2019) and reduces its reabsorption (Moriceau et al., 2000).BAs are synthesized from cholesterol. Therefore, appropriate DF intake can decrease cholesterol (Chen et al., 2018) and hepatic steatosis (Brockman et al., 2014). However, the effect of excessive DF intake on fish, which occurs with an increasing number of plant ingredients being included in the diet, has not received enough attention.

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Lipid metabolism and plasma metabolomics of juvenile largemouth bass Micropterus salmoides were affected by dietary oxidized fish oil

Cited by 69 publications

References 50 publications

Dietary lipid levels affected growth performance, lipid accumulation, inflammatory response and apoptosis of japanese seabass (lateolabraxjaponicus)

Dietary lipid levels affected growth performance, lipid accumulation, inflammatory response and apoptosis of japanese seabass (lateolabraxjaponicus)

Dietary Supplementation of Astaxanthin Improved the Growth Performance, Antioxidant Ability and Immune Response of Juvenile Largemouth Bass (Micropterus salmoides) Fed High-Fat Diet

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

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