Lipid Metabolism in Plants Under High Temperature

Bhattacharya, A.

doi:10.1016/b978-0-12-817562-0.00004-5

Cited by 2 publications

(2 citation statements)

References 372 publications

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“…Cytidine 5′-diphosphocholine, better known as Citicoline, already finds its therapeutic use in systemic neurodegenerations, such as AD, PD and ischemia. In fact, citicoline, since its chemical structure resembles a precursor of phosphatidylcholine, has several action mechanisms, including phospholipid homeostasis, redox homeostasis, mitochondrial dynamics, cholinergic and dopaminergic neurotransmission [ 204 , 205 , 206 ]. Therefore, given the similarities between the neurodegeneration pattern of glaucoma and other neurodegenerative diseases (e.g., AD), citicoline has become increasingly used also in glaucoma studies showing its ability to stabilize the plasma membrane of RGC axons and to counteract glutamate excitotoxicity [ 207 ], as well as to control oxidative stress.…”

Section: Neuroprotectionmentioning

confidence: 99%

Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention

Vernazza

Oddone

Tirendi

et al. 2021

IJMS

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Retinal ganglion cells (RGCs) are a population of neurons of the central nervous system (CNS) extending with their soma to the inner retina and with their axons to the optic nerve. Glaucoma represents a group of neurodegenerative diseases where the slow progressive death of RGCs results in a permanent loss of vision. To date, although Intra Ocular Pressure (IOP) is considered the main therapeutic target, the precise mechanisms by which RGCs die in glaucoma have not yet been clarified. In fact, Primary Open Angle Glaucoma (POAG), which is the most common glaucoma form, also occurs without elevated IOP. This present review provides a summary of some pathological conditions, i.e., axonal transport blockade, glutamate excitotoxicity and changes in pro-inflammatory cytokines along the RGC projection, all involved in the glaucoma cascade. Moreover, neuro-protective therapeutic approaches, which aim to improve RGC degeneration, have also been taken into consideration.

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Section: Neuroprotectionmentioning

confidence: 99%

Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention

Vernazza

Oddone

Tirendi

et al. 2021

IJMS

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“…As a result, we identified four lipid pathways with a p-value < 0.05 of significance. The pathway displaying a clearer perturbation was the glycerophospholipid metabolism, which is ubiquitous in nature and is a key component of the lipid bilayer of cells and involved in the metabolism of cell signaling (Bhattacharya, 2019). Phosphatidylinositol metabolism was also perturbed and also is involved in the signaling system.…”

Section: Identification Of Lipid Pathways Altered During Floral Trans...mentioning

confidence: 99%

Identification of Bioactive Molecules in the Control of Flowering Time

Tamayo¹

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La ciencia, si algo tiene que me gusta, es su indudable parte colaborativa. Esta tesis lleva muchos nombres de aquellos que han participado de una manera directa o indirectamente.En especial, hay un grupo de personas esenciales quienes han sido mis guías en el laberinto científico en lo que supone plantearse una pregunta y ser capaz de formular respuestas adecuadas. Gracias por la oportunidad y la fe que habéis puesto en mí.Durante aquellas clases del máster en las que ese profesor simpático hizo que me interesara por otras ramas de la biotecnología vegetal y que desde que empecé la tesis ha estado siempre disponible para discutir, hipotetizar, celebrar pequeñas alegrías y por plantearme otros puntos de vista a mis hipótesis. Gracias, Paco.Por toda mi formación y abrirme un mundo de posibilidades, por descubrirme nuevas áreas de la biología molecular, enseñarme a trabajar en el laboratorio y dar juntos mis primeros pasos en la ciencia, animarme a no conformarme e intentar mejorar, por saber escuchar cuando lo he necesitado y por confiar en mí. Gracias, Reyes.A todos mis compañeros del laboratorio 1.07 y 1.09. Todos vosotros habéis participado en el día a día y año tras año, habéis hecho que tengamos un ambiente excelente en el que hemos disfrutado el tiempo juntos y que trabajar sea muy fácil. Es un lujo contar con compañeros como vosotros. Especialmente a Cristina por toda la ayuda, asesoramiento, consejos y la inspiradora pasión que transmite al discutir proyectos o ideas. Gracias.A special thanks to Thomas for hosting me in his lab. He was very welcoming with his kindness, humility and closeness with which he treated me from day one, and without his support during and after my research stay, this work would have been very different. I also thank Ilara for her patience, constant support and willingness to help me wherever I needed it. From her I have received more of a friendship than a collaborator.A mi familia, por el continuo apoyo durante toda mi vida. A Mar, por ser un ancla en la tormenta, enseñarme y compartir el mismo sendero. A Simba y Pumba, mis compañeros de vida perruna, quienes con un paseo me quitaban todas las preocupaciones.

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Lipid Metabolism in Plants Under High Temperature

Cited by 2 publications

References 372 publications

Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention

Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention

Identification of Bioactive Molecules in the Control of Flowering Time

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