Lipid Metabolism of Puppies as Affected by Kind and Amount of Fat and of Dietary Carbohydrate

Wiese, Hilda F.; Bennett, Mildred J.; Coon, Edmund; Yamanaka, William K.

doi:10.1093/jn/86.3.271

Cited by 6 publications

(2 citation statements)

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“…Experimental conditions. Beagle pup pies from the time of weaning were fed isocaloric diets which were considered fully adequate in calories, protein, vitamins, and minerals, but differed in the kind and amount of fat (17). Five diets were de ficient in linoleic acid, one having 30% of the calories as hydrogenated coconut oil, one low in fat (1% of the calories), and 3 diets low in fat to which sufficient linolenic, oleic, or arachidonic acid was added to supply 2% of the calories.…”

Section: Conditions and Methodsmentioning

confidence: 99%

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Skin Lipids of Puppies as Affected by Kind and Amount of Dietary Fat

Wiese¹,

Yamanaka²,

Coon³

et al. 1966

The Journal of Nutrition

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Clinical evidence of a dietary requirement for linoleic acid in main tenance of a healthy skin prompted a study of fatty acid distributions in skin of 84 young dogs fed diets with and without linoleic acid. When weanling puppies were fed diets deficient in linoleic acid for 2 months, monoene fatty acids in whole skin greatly exceeded levels for saturated fatty acids. Linoleic and arachidonic acid levels were lower than for newborn puppies. Levels of these fatty acids decreased further in skin and serum after 4 months when definite deficiency signs were evident, but levels remained approximately the same during longer feeding periods. Small amounts of linoleic acid were always present in skin and serum. Step-by-step increases in dietary linoleate were reflected in increased levels of this fatty acid in triglycÃ©rides, cholesterol esters, and phospholipids in skin and serum. During linoleic acid-deficient states, 5,8,11-eicosatrienoic acid was always present in serum, but it was observed infrequently in skin and only in the phospholipid fraction. In deficient states arachi donic acid was present in most serum silicic acid fractions but appeared infrequently in small amounts only in skin phospholipids. When ethyl arachidonate was fed for 2 months after weaning, it was observed in skin and serum, but during recovery from the linoleic deficient state, it was not noted in skin after a 2-month feeding period. Phospholipids make up a small fraction of skin lipids, but changes in their fatty acid patterns appear to reflect alterations which occur in epidermal cells during a dietary deficiency of linoleic acid.

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Section: Conditions and Methodsmentioning

confidence: 99%

“…Diets were fed at the normal caloric level for growing puppies (17). Immunization and care of the animals also were the same as previously described (17).…”

Section: Conditions and Methodsmentioning

confidence: 99%