“…Although MLVs can be used to entrap and deliver various types of molecules, they tend to have shorter circulation half-lives. 25,26 There have a been number of reports in the literature examining the addition of silicon-based compounds, most notably silicones, to liposome structures. [27][28][29] These siliconbased compounds were not part of the lipids themselves but were added to stabilize/protect the liposomal structures.…”
Hybrid siloxane-phosphocholines (SiPCs) are a unique class of lipids that spontaneously form unilamellar vesicles (ULVs) that are ∼100 nm in diameter upon exposure to aqueous media without the need for extrusion and can be used as delivery vehicles.
“…Although MLVs can be used to entrap and deliver various types of molecules, they tend to have shorter circulation half-lives. 25,26 There have a been number of reports in the literature examining the addition of silicon-based compounds, most notably silicones, to liposome structures. [27][28][29] These siliconbased compounds were not part of the lipids themselves but were added to stabilize/protect the liposomal structures.…”
Hybrid siloxane-phosphocholines (SiPCs) are a unique class of lipids that spontaneously form unilamellar vesicles (ULVs) that are ∼100 nm in diameter upon exposure to aqueous media without the need for extrusion and can be used as delivery vehicles.
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