Lipid Profile Biomarkers Implication in Preschool Organizations Menu Assessment

Abstract

The search for nutrition biomarkers, forming the so-called metabotype, is of great importance for assessing the nutrition model and its impact on human health. Currently, there is a large number of studies conducted on the metabolomic diet fat component profile; scientists are studying the acylcarnitines spectrum depending on the diet type, increasingly. Still, there is deficiency of the lipid profile biomarkers importance in the preschool organization menu assessment. The aim of the study was to determine the lipid profile biomarkers importance in assessing the preschool children menu. The researchers evaluated the menu of two preschool organizations of the Sverdlovsk region and analyzed the metabolic profile of 190 children attending it. The greatest excess of saturated and unsaturated fatty acids content, the sources of which were animal products in the menu of one of the preschool organizations, is relatable to a higher content of medium-chain and long-chain acylcarnitines in the children blood serum; in turn, there is a higher content of short-chain acylcarnitines in serum in the course of a higher amount of vegetable fats in the diet. Acylcarnitines can act not only as markers of rational nutrition, but also as risk factors for the development of a whole disease range. Therefore, the data obtained in the study on the acylcarnitine content in children with different amounts of saturated and unsaturated fatty acids in the diet can act as biomarkers of an unbalanced diet for the fat component with subsequent correction.