Lipid profile in middle class Bengali population of Kolkata

Abstract

Fasting samples of 1396 apparently healthy, middle class Bengali population of Kolkata, West Bengal were tested for total cholesterol, triglyceddes, high density lipoprotein cholesterol, low density lipoprotein cholesterol and very low density lipoprotein cholesterol, over a pedod of three years. The values obtained were (in mg/dl) 190 + 33, 132 + 42, 53 + 10, 116 :!: 30 and 21 + 7 respectively. When these subjects were grouped according to the age and sex, no appreciable difference were observed between most of the groups. Tdglyceride was found to be low and HDL cholesterol was high in women below 30 years when compared with men of similar age. Beyond 60 years, cholesterol level as well as low density lipoprotein cholesterol was found to be gradually increased in case of women. Besides these changes, other minor differences were not statistically significant. It is suggested that the lipid values of the present study should be taken as a base parameters and the clinical evaluation be made on the basis of these finding. KEY WORDSLipid profile, lipoproteins, lipid triad index, epidemiological study.

To Establish the Reference Intervals of Lipid Profile in Punjab

“…Decade wise analysis of triglycerides reveals an increase in their level in females with age and the change is significant (P = 0.040). Similar pattern has been observed in various Indian studies conducted in western Maharashtra by Durgawale et al [13] and in Kolkata by Goswami and Bandyopadhyay [12]. Serum VLDL-C level follows the same pattern as Serum triglycerides.…”

“…Decade wise analysis also reveals an increase in LDL-C levels with age in both males and females but the change is not significant (Table 4). Similar changes have also been observed in decade wise analysis of LDL-C levels in Bengali population of Kolkata [12]. Also, the LDL-C levels outside the reference range are increasing with age with maximum in the 4th decade in males and in the 7th decade in females.…”

“…High LDL-C levels in females (133.4 ± 34.8 mg/dl) have been seen as compared to males (116.5 ± 27.6 mg/dl) in a similar study done in Kolkata [12] in 2003. On the contrary, the mean LDL-C levels in the study conducted on lipid profile in Andhra Pradesh [15] reveals lower level of LDL-C in females (99.2 ± 30.6 mg/dl) as compared to males (102.4 ± 29.5 mg/dl).…”

“…The level of HDL-C in females has also been found to decrease with advancing age ([60 years) in the study done on lipid profile in western Maharashtra [13] (44.0 ± 6.3 mg/dl) as well as in Kolkata [12] (49.5 ± 6.6 mg/dl) in the same age group. Also, with increasing age, the number of females having HDL-C level lower than the reference range is increasing with maximum in the age group above 70 years.…”

“…Available global data have clearly established the relationship of lipids and other risk factors with cardiovascular and cerebrovascular events [3][4][5][6][7][8][9][10][11]. It is therefore essential to establish a reference range of the values of serum lipids for a given population as only a few studies have been carried out in other regions of India [12][13][14][15].…”