Lipid Storage Myopathy in Behçet's Disease: A Rare Cause of Elevated Serum Creatine Kinases Levels

Abstract

Muscular involvement in Behçet's disease is rare and there are only a few case reports in the literature. The causes of elevated muscle enzymes in a patient with Behcet's disease are many, including myositis, drug-induced myopathy, metabolic myopathy, and the disease itself. We herein have defined an algorithmic approach to a patient with Behcet's disease and elevated muscle enzymes and report a case of coexisting of lipid storage myopathy.

Unilateral Symptomatic Intracranial Arterial Stenosis and Myopathy in an Adolescent with Graves Disease: A Case Report of an High-resolution Magnetic Resonance Imaging Study

“…16,17 The other possibility might be that the same immune dysfunction mechanism induced by GD is responsible for both intracranial arterial stenosis and thyroid myopathy, because they continue to constantly and gradually develop despite normalization of the T3, T4, and TSH levels, with only the antibody against the thyroid remaining elevated. This is similar to another 2 cases that LSM was secondary to Behcet disease 18 and that polymyositis was associated with GD. 19 Therefore, this case suggested that pathologic manifestations of chronic hyperthyroidism myopathy might have been presented with pure intramuscular lipid deposition at disease onset.…”