Lipid Tubules: A Paradigm for Molecularly Engineered Structures

Schnur, Joel M.

doi:10.1126/science.262.5140.1669

Cited by 719 publications

(539 citation statements)

References 56 publications

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“…The defect regions are stabilized by the segregation of SDS molecules to compensate the highmembrane curvature. As for a surfactant, its preferred packing [16][17][18][19][20] . The HGM molecule has similar area of head group and tail with CPP B1.…”

Section: Discussionmentioning

confidence: 99%

Novel polymer-free iridescent lamellar hydrogel for two-dimensional confined growth of ultrathin gold membranes

et al. 2014

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Hydrogels are generally thought to be formed by nano-to micrometre-scale fibres or polymer chains, either physically branched or entangled with each other to trap water. Although there are also anisotropic hydrogels with apparently ordered structures, they are essentially polymer fibre/discrete polymer chains-based network without exception. Here we present a type of polymer-free anisotropic lamellar hydrogels composed of 100-nm-thick water layers sandwiched by two bilayer membranes of a self-assembled nonionic surfactant, hexadecylglyceryl maleate. The hydrogels appear iridescent as a result of Bragg's reflection of visible light from the periodic lamellar plane. The particular lamellar hydrogel with extremely wide water spacing was used as a soft two-dimensional template to synthesize singlecrystalline nanosheets in the confined two-dimensional space. As a consequence, flexible, ultrathin and large area single-crystalline gold membranes with atomically flat surface were produced in the hydrogel. The optical and electrical properties were detected on a single gold membrane.

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Section: Discussionmentioning

confidence: 99%

Novel polymer-free iridescent lamellar hydrogel for two-dimensional confined growth of ultrathin gold membranes

et al. 2014

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“…37 Synthetic methodologies of organic nanotubes are roughly classified into three groups: (i) self-assembly, 15,38 (ii) hollow sculpture, 39,40 and (iii) template methods (Fig. 4).…”

Section: Synthetic Methodologies Of Organic Nanotubesmentioning

confidence: 99%

Self‐assembled organic nanotubes: Toward attoliter chemistry

Shimizu

2008

J. Polym. Sci. A Polym. Chem.

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Diverse chemical functionalization of the inner and outer surfaces of the nanotubes enables us to sense and visualize the encapsulation and transport behavior of biomacromolecular guests. The event occurs specifically in attoliter volume nanospace inside the hollow cylinder of the nanotubes. Comparison of the organic nanotube history with that of well‐known carbon nanotubes and a variety of molecular building blocks as tube‐forming compounds were first introduced. Asymmetric organic nanotubes with different inner and outer surfaces were discussed in terms of molecular design, immobilization of functional moieties, and molecular packing. Finally, the practical examples of the organic nanotubes as a nanocontainer, nanochannel, and nanopipette were also described to feature the concept of “attoliter chemistry.” © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 2601–2611, 2008

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“…The inclusion of hydrophobic pyrene into the cavity of CD is expected to make the focal moiety hydrophilic because of the hydrophilic outer surface of CD, and consequently the volume ratio of the hydrophilic and hydrophobic moieties of the building blocks is changed. The dendron building blocks with the focal CD-pyrene are expected to form bilayer structures, which undergo helical transformation and then form tubular architecture after a similar mechanism of the nanotube formation of lipids (8,12,14,32).…”

Section: Resultsmentioning

confidence: 99%

Cyclodextrin-covered organic nanotubes derived from self-assembly of dendrons and their supramolecular transformation

Park

Lee

et al. 2006

Proc. Natl. Acad. Sci. U.S.A.

133

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The dendritic building blocks with a focal pyrene unit self-organize into vesicles in aqueous phase. The in situ inclusion of the focal pyrene units into the cavity of ␤-or ␥-cyclodextrin (CD) induces self-assembled organic nanotubes with an average outer diameter of Ϸ45 nm and inner diameter of 22 nm. The surface of the nanotube is covered with CD. Therefore, the functional group on the surface of the nanotube is controlled simply by modifying the functionality of CD. The removal of CD from the nanotube with poly(propylene glycol) reversibly generates vesicles. This work provides an efficient methodology not only to create an additional class of CD-covered organic nanotubes but also to exhibit reversible transformation of nanotubes and vesicles triggered by the motifs of dendron self-assembly, CD inclusion, and pseudorotaxane formation.vesicle ͉ amphiphile S elf-assembly and transformation of biological or synthetic macromolecules in a wide range of scientific fields are crucial subjects for the achievement of well defined nanostructures and the precise control of the function of supramolecules at the molecular level (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). A multitude of biological or chemical assemblies including vesicle, tubule, fibril, and viral helical coats perform numerous biochemical operations in nature. In particular, vesicular and tubular assemblies are of much interest because of their unique characteristics as a biomimetic system, carrier for drug or gene, biochemical sensor, electronic or photonic material, nanoreactor, and template for hybrid structure (9-18). Therefore, in these viewpoints, self-assembly of synthetic building blocks by noncovalent interactions is expected to provide a unique methodology for creating supramolecular functional materials (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27).Self-organization of dendrons (6) into supramolecular assemblies has been demonstrated in a thermotropic fashion (19,27), in aqueous phase (21-25), in organic media (20,22,23,26), and at solid-liquid interface (26). Recently, we reported that the amide dendrons can self-organize in various conditions to exhibit a multiplicity of architectures and functions (22-26). For the preparation of self-assembling nanomaterials, we designed the amide dendritic building blocks consisting of amide branches for hydrogen bonding, carboxyl functionality at the focal point, and alkyl tails for the stabilization of assembled structures by van der Waals interaction (22). Particularly, it was suggested that the dimeric form of the amide dendron, induced by secondary interactions such as hydrogen bonding and -interaction at the focal functional units, is the primary building block in the self-aggregation process in organic media (22,23,26). In addition, the amphiphilic nature of these amide dendritic building blocks provides an opportunity for the formation of various self-assembled nanostructures in aqueous phase. For example, we reported that the transition of the self-organiz...

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Lipid Tubules: A Paradigm for Molecularly Engineered Structures

Cited by 719 publications

References 56 publications

Novel polymer-free iridescent lamellar hydrogel for two-dimensional confined growth of ultrathin gold membranes

Novel polymer-free iridescent lamellar hydrogel for two-dimensional confined growth of ultrathin gold membranes

Self‐assembled organic nanotubes: Toward attoliter chemistry

Cyclodextrin-covered organic nanotubes derived from self-assembly of dendrons and their supramolecular transformation

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