Lipidological competence centres and networks: Future perspectives to improve healthcare of patients with disorders of lipid metabolism

Heigl, Franz; Pflederer, Tobias; Schettler, Volker; Grützmacher, P.; Julius, Ulrich; Ringel, J; David-Walek, Tilmann; Hettich, R; Lotz, N.; Reeg, Harduin; Graf, Markus; Klör, Hans‐Ulrich

doi:10.1016/j.atherosclerosissup.2017.05.014

Cited by 5 publications

(5 citation statements)

References 18 publications

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“…Patient management could benefit from professional networks through facilitated transitory processes (i.e., between medical specialists, general practitioners, and lipid ambulances) and diagnosis of rare lipid disorders through lipid competence centers. Furthermore, networks could promote inter- and intradisciplinary exchange and continued training (e.g., qualification as certified “lipidologist”) [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results from a Nationwide Online Survey

Beier

Wolf²,

Willfeld

et al. 2022

Adv Ther

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Introduction Effective hypercholesterolemia management is essential in primary prevention of cardiovascular events. The objective of PROCYON was to assess the perception on hypercholesterolemia management in primary prevention and to identify reasons for insufficient target attainment in clinical practice in Germany. Methods PROCYON was a two-part online survey including a patient questionnaire on treatment status and disease knowledge and a physician questionnaire on guideline awareness and patient management. A conjoint analysis on the relative importance of cardiovascular risk factors was incorporated. Results Of 3798 primary prevention patients included, 1632 (43.0%) received lipid-lowering medication. Of these, 790 (48.4%) reported improved low-density lipoprotein cholesterol (LDL-C) levels, 670 (41.1%) reported no improvement, and 172 (10.5%) had no information. Of the treated patients with ( N ′ = 790) and without ( N ′ = 670) improvement, 52.4% vs. 47.9% were on their initial drug and dose, 8.9% vs. 9.0% received multiple drug therapy, 34.7% vs. 38.8% reported a dose change, and 16.0% vs. 19.4% had discontinued at least one drug (multiple answers). In total, 109 physicians participated. In the conjoint analysis, LDL-C level was attributed the highest relative importance (32.0%), followed by diabetes (24.5%) and systolic blood pressure (15.8%). Lipid-lowering therapy is initiated at an LDL-C level > 150 mg/dl by 63 physicians (57.8%). One third ( n = 35; 32.1%) stated that ≥ 60% of their primary prevention patients do not receive lipid-lowering medication. Conclusion PROCYON suggests a need for consequent LDL-C target-based treatment implementation. Supplementary Information The online version contains supplementary material available at 10.1007/s12325-022-02266-3.

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Section: Discussionmentioning

confidence: 99%

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results from a Nationwide Online Survey

Beier

Wolf²,

Willfeld

et al. 2022

Adv Ther

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“…Interdisciplinary patient management could overcome these issues and needs to be strengthened. In this respect, lipidological competence centers and networks as suggested by Heigl et al deserve increased attention [ 22 ]. In PROCYON, 5.5% of patients were referred to a lipid clinic.…”

Section: Discussionmentioning

confidence: 99%

“…In general, most patients in secondary prevention could probably benefit by referrals to lipid clinics and tighter cooperation between GPs and lipid clinics could probably result in a significant improvement in secondary prevention. Therefore, the German Lipid Association (DGFF) already promotes the training and qualification as a certified lipidologist [ 22 ]. Networking of lipidologists, GPs, and specialists will increase awareness and target attainment each region.…”

Section: Discussionmentioning

confidence: 99%

Different Perspectives of Patients and Physicians on LDL-C Target Achievement in the Treatment of Hypercholesterolemia: Results on Secondary Prevention from the German PROCYON Survey

Makhmudova

Wolf²,

Willfeld

et al. 2022

Adv Ther

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Aims Low-density lipoprotein cholesterol (LDL-C) reduction in hypercholesterolemia patients at very high cardiovascular (CV) risk is essential in preventing future CV events. The objective was to assess the perception on hypercholesterolemia management in secondary prevention in Germany. Methods PROCYON was a two-part online survey, including a patient questionnaire as well as a physician questionnaire. Results A total of 109 general practitioners, internists, and cardiologists participated. The current ESC/EAS recommendation for high-risk patients is followed by 19.3% of the physicians. The majority (80.7%) reported an LDL-C target failure rate of at least 30%. More than two thirds (71.6%) have stated treating less than half of their patients with the maximum approved statin dose. The survey included 1696 secondary prevention patients. The majority (86.7%) consult their general practitioner for hypercholesterolemia; 54.0% consult a cardiologist (multiple answers allowed). Most patients (87.0%) were receiving lipid-lowering medication. Among these, 800 (54.2%) reported improved LDL-C levels since diagnosis, 569 (38.6%) reported no improvement, and 106 (7.2%) had no information. Of the treated patients with ( N ’ = 800) and without ( N ’ = 569) improvement, 34.3% vs. 37.3% were on their initial drug and dose, 24.8% vs. 23.7% received multiple drug therapy, 48.9% vs. 48.9% reported a dose change, and 16.1% vs. 14.2% had discontinued at least one drug (multiple answers). Disease knowledge was rated as good or very good by 29.8% of patients. Conclusion PROCYON demonstrated insufficient ESC/EAS guideline implementation regarding target levels and therapeutic escalation strategies. Furthermore, a lack of specialist involvement and patient education was identified.

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“…Furthermore, networks could promote inter-and intradisciplinary exchange and continued training (e.g. quali cation as certi ed "lipidologist") [23] .…”

Section: Discussionmentioning

confidence: 99%

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results From a Nationwide Online Survey

Beier

Wolf²,

Stein

et al. 2022

Preprint

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Aims: Effective hypercholesterolemia management is essential in primary prevention of cardiovascular events. PROCYON assessed the perception on hypercholesterolemia management in clinical practice in Germany.Methods: The online survey included a patient questionnaire on treatment status and disease knowledge and a physician questionnaire on guideline awareness and patient management together with a conjoint analysis on cardiovascular risk factors.Results: Of 3,798 patients included, 1,632 (43.0%) received lipid-lowering medication. Of these, 790 (48.4%) reported improved low-density lipoprotein cholesterol (LDL-C) levels, 670 (41.1%) reported no improvement, and 172 (10.5%) had no information. Of the treated patients with (N’=790) and without (N’=670) improvement, 52.4% vs. 47.9% were on their initial drug and dose, 8.9% vs. 9.0% received multiple drug therapy, 34.7% vs. 38.8% reported a dose change, and 16.0% vs. 19.4% had discontinued at least one drug (multiple answers).In total, 109 physicians participated. LDL-C level was attributed the highest relative importance (32.0%), followed by diabetes (24.5%) and systolic blood pressure (15.8%). Lipid-lowering therapy is initiated at an LDL-C level >150 mg/dL by 63 physicians (57.8%). One third (n=35; 32.1%) stated that ≥60% of their primary prevention patients do not receive lipid-lowering medication.Conclusion: PROCYON identified a need for consequent LDL-C target-based treatment implementation.

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Lipidological competence centres and networks: Future perspectives to improve healthcare of patients with disorders of lipid metabolism

Cited by 5 publications

References 18 publications

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results from a Nationwide Online Survey

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results from a Nationwide Online Survey

Different Perspectives of Patients and Physicians on LDL-C Target Achievement in the Treatment of Hypercholesterolemia: Results on Secondary Prevention from the German PROCYON Survey

Patient and Physician Reported Perception on Hypercholesterolemia Management in Primary Prevention in Germany: Results From a Nationwide Online Survey

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