2013
DOI: 10.1016/j.foodres.2013.10.001
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Lipidomic study of olive fruit and oil using TiO2 nanoparticle based matrix solid-phase dispersion and MALDI-TOF/MS

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Cited by 32 publications
(16 citation statements)
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“…Therefore, there are extensive efforts to substitute traditional matrices, or to improve their properties, either by replacing organic compounds with nanoparticles of specific optical and electrochemical properties, or by an addition of nanoparticles to organic matrices. Among them, metals, and metal-oxide nanoparticles [9][10][11][12] have been applied for MALDI-TOF MS or for the mass spectrometry investigation of various molecules, including peptides, lipids, vitamins, carbohydrates, steroids/hormones, and other compounds [13][14][15]. Carbon-based materials such as graphene and carbon nanotubes have been tested as substrates to overcome the drawbacks of organic matrices [16].…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, there are extensive efforts to substitute traditional matrices, or to improve their properties, either by replacing organic compounds with nanoparticles of specific optical and electrochemical properties, or by an addition of nanoparticles to organic matrices. Among them, metals, and metal-oxide nanoparticles [9][10][11][12] have been applied for MALDI-TOF MS or for the mass spectrometry investigation of various molecules, including peptides, lipids, vitamins, carbohydrates, steroids/hormones, and other compounds [13][14][15]. Carbon-based materials such as graphene and carbon nanotubes have been tested as substrates to overcome the drawbacks of organic matrices [16].…”
Section: Introductionmentioning
confidence: 99%
“…Shen and co-workers [75] optimized a matrix solid-phase dispersion (MSPD) procedure to extract several phospholipids from olive fruit and oil samples, exploiting the ability of the sorbent (TiO 2 nanoparticles) to selectively interact with the phosphate group of the analyte by a chelating bidentate bond. After elution, MALDI-TOF analysis in both positive and negative ion modes was performed.…”
Section: Oilsmentioning
confidence: 99%
“…A related approach is matrix solid-phase dispersion. For example, titanium dioxide nanoparticles (TNPs) were used as sorbent to bind phospholipids from olive fruit and oil in a lipidomics study [ 33 ]. Phospholipids are nutrients involved in lipid digestion, absorption, transport and many other signaling pathways.…”
Section: Nanoparticles For Metabolomics Sample Preparationmentioning
confidence: 99%