2020
DOI: 10.12688/f1000research.19598.5
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Lipidomics reveal the protective effects of a vegetable-derived isothiocyanate against retinal degeneration

Abstract: Background: Age-related macular degeneration (AMD) is a leading cause of blindness in the ageing population. Without effective treatment strategies that can prevent disease progression, there is an urgent need for novel therapeutic interventions to reduce the burden of vision loss and improve patients’ quality of life. Dysfunctional innate immune responses to oxidative stress observed in AMD can be caused by the formation of oxidised lipids, whilst polyunsaturated fatty acids have shown to increase the risk of… Show more

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