Lipids: Absorption and Transport

Lichtenstein, Alice H.; Jones, Peter J.H.

doi:10.1002/9781119946045.ch9

Cited by 19 publications

(15 citation statements)

References 96 publications

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“…They loaded the optical probe, DiI on the surface of FA-LDLs and native LDLs to visualize their cellular uptake by KB cells (FRþ), CHO cells (FRÀ), HT-1080 cells (FRÀ), and HepG2 Table I. Types of lipoproteins and their physico-chemical properties (Brody 1999;Dasgupta and Wahed, 2014;Lichtenstein and Jones, 2012;Liu et al, 2006).…”

Section: Lipoproteinsmentioning

confidence: 99%

Co‐opting biology to deliver drugs

Yousefpour

Chilkoti

2014

Biotech & Bioengineering

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The goal of drug delivery is to improve the safety and therapeutic efficacy of drugs. This review focuses on delivery platforms that are either derived from endogenous pathways, long-circulating biomolecules and cells or that piggyback onto long-circulating biomolecules and cells. The first class of such platforms is protein-based delivery systems—albumin, transferrin, and fusion to the Fc domain of antibodies—that have a long-circulation half-life and are designed to transport different molecules. The second class is lipid-based delivery systems—lipoproteins and exosomes—that are naturally occurring circulating lipid particles. The third class is cell-based delivery systems—erythrocytes, macrophages, and platelets—that have evolved, for reasons central to their function, to exhibit a long life-time in the body. The last class is small molecule-based delivery systems that include folic acid. This paper reviews the biology of these systems, their application in drug delivery, and the promises and limitations of these endogenous systems for drug delivery.

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Section: Lipoproteinsmentioning

confidence: 99%

Co‐opting biology to deliver drugs

Yousefpour

Chilkoti

2014

Biotech & Bioengineering

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“…The maximum level of daily total fat needed is 30% of the total energy, which includes 10% of saturated fatty acids (SFA), 10% of monounsaturated fatty acids (MUFA), and 10% of polyunsaturated fatty acids (PUFA). Cells require energy to meet the nutritional needs of breast milk production, and the enzyme lipase in fat cells breaks down triglycerides into glycerol and free fatty acids and releases them into the blood vessels [25]. Most of the free fatty acids return into circulation, allowing the absorption of the lipoprotein triacylglycerol fatty acid to produce milk fat [26].…”

Section: Discussionmentioning

confidence: 99%

The effect of organic quail egg supplementation on the blood lipid profile of white mice (Rattus Norvegicus L.) during the lactation period

purba¹,

Saraswati²,

Isdadiyanto³

2018

J. Phys.: Conf. Ser.

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The effect of organic quail egg supplementation on the blood lipid profile of white mice (Rattus Norvegicus L.) during the lactation period Abstract.Background: Quail eggs contain a considerable amount of complete nutritional sources such as carbohydrates, proteins, fats, and micronutrients. However, they also have a high cholesterol level, which can potentially cause atherosclerosis and chronic heart diseases. The response of the body to foods containing is influenced by factors such as ethnicity, genetics, and hormonal and nutrient status of the consumer. The cholesterol level of quail eggs can be reduced by manipulating the feed using supplemental organic feed. Organic quail eggs have been believed to correct the lipid profile of white mice during the lactation phase. Purpose: The aim of this study was to analyze the effect of feed containing organic quail eggs on the blood lipid profile of white mice (Rattus norvegicus L.) during the lactation phase. Materials and Methods: This experimental study was conducted using a completely randomized design with four experiments and five repetitions. Experimental mice: T0 mice were used as control; T1 mice were supplemented with quail eggs produced by quails that were fed with standard feed; T2 mice were supplemented with eggs produced by quails fed with standard organic feed; and T3 mice were supplemented with eggs produced by quails fed with organic feed with the addition of cassava leaf flour, mackerel flour, and turmeric powder. Quail egg supplementation was administered to the mice from the early pregnancy period till the end of the lactation phase. The acquired data were analyzed using ANOVA. SPSS version 16.0 software for Windows was used for data analyses. Results and summary: Feeding the white mice with different compositions of organic quail egg supplements had no effect on the consumption of feed and water, body weight, and lipid profile (including total cholesterol, LDL, HDL, and triglyceride) during the lactation phase (P > 0.05).

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“…Lipids are also source of fat soluble vitamins and sterols. Lipid consumption recommended for a daily intake, should be about 20% to 35% for a 2000 calorie diet, this represent, 56g to 78g of fat, or for 3000 calorie diet, this represents about 83 to 117g of fat [19].…”

Section: Monthmentioning

confidence: 99%