Lipodermatosclerosis in patients with diffuse connective tissue diseases

Gonzalez, Fernanda; Magalhães, Fernanda Pedreira; Freitas, Alice Pontes Vilas Boas; Filho, Humberto Castro Lima; Santiago, Mittermayer B.

doi:10.1016/j.ejim.2005.11.030

Cited by 9 publications

(5 citation statements)

References 5 publications

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“…Dias Gonzalez et al., described three patients with connective tissue diseases (the first one with Lupus erythematosus; the second one with superposition of rheumatoid arthritis, Sjőgren's syndrome, morphea; and the third one with Calcinosis, Raynaud phenomenon, Esophageal dysmotility, Sclerodactyly and Teleangiectasia [CREST] syndrome) that developed LDS (25). They suggested that a work‐up for antiphospholipid antibodies could be of potential help in cases of LDS with obscure etiopathogenesis, nonrelated to venous abnormalities.…”

Section: Clinical Presentation Of Lds: Classificationmentioning

confidence: 99%

Lipodermatosclerosis

Miteva

Romanelli

Kirsner

2010

Dermatologic Therapy

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The most commonly recognized form of lipodermatosclerosis (LDS), chronic LDS presents with induration and hyperpigmentation of the skin involving the one or both of the lower legs in a characteristic "inverted champagne bottle" appearance. Associated with venous insufficiency, LDS is most common in middle aged women. In addition to chronic LDS, an acute form may also occur and is often misdiagnosed as cellulitis, inflammatory morphea, or erythema nodosum. The "acute" refers to the symptoms present that are exquisite pain. Treatment of LDS is based on the clinical presentation with compression therapy as the mainstay of treatment if tolerated. For acute LDS, patients often cannot tolerate compression therapy due to pain. We advise the use of fibrinolytic therapy, if available, until the patient can tolerate compression stockings.

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Section: Clinical Presentation Of Lds: Classificationmentioning

confidence: 99%

Lipodermatosclerosis

Miteva

Romanelli

Kirsner

2010

Dermatologic Therapy

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“…Conversely, we cannot exclude the possibility that our patient has an atypical ulcerative form of lipodermatosclerosis, panniculitis that is eventually observed, in association with diffuse connective tissue diseases, including SSc. 9 Another rare hypertrophic form of SSc, called keloidal scleroderma, has clinical features that are easily distinguished from ENV.…”

Section: Discussionmentioning

confidence: 99%

Concomitance of Elephantiasis Nostras Verrucosa and Systemic Sclerosis

et al. 2020

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“…Lipodermatosclerosis (LDS) or sclerosing panniculitis is a chronic fibrosing condition that usually appears in middle-aged or elderly women, often with a history of venous insufficiency or arterial ischemia. [1][2][3][4][5] It begins as painful erythematous, poorly demarcated plaques involving one or both lower legs above the medial malleolus. The chronic phase most often occurs as hyperpigmented, indurated, depressed skin.…”

Section: Introductionmentioning

confidence: 99%

“…Ulceration may develop in about 13% of cases. 1,[4][5][6][7][8][9][10][11] The early lesions of LDS can mimic other diseases including cellulitis, erythema nodosum (EN), stasis dermatitis, and medium-sized vasculitis. 2,3 Despite the well-documented clinical findings, the microscopic changes have not been extensively characterized in published works.…”

Section: Introductionmentioning

confidence: 99%