1982
DOI: 10.1111/j.1365-2133.1982.tb04541.x
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Lipodystrophia centrifugalis abdominalis infantilis

Abstract: We describe the first case of lipodystrophia centrifugalis abdominalis infantilis to occur outside Japan. A 7-year-old Chinese boy presented with the classical features, which include the early onset of localized depression of the skin of the abdomen, centrifugal progression of the skin lesion and an erythematous scaling advancing edge. The subcutaneous fat is decreased in the depressed areas.

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Cited by 22 publications
(17 citation statements)
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“…Mild perivascular dermal infiltrate has been reported at the leading edge of LCAI 16,17 . The brisk, deep dermal and lobular lymphocytic infiltrate seen in our case exceeds that presented in other reports.…”
Section: Discussioncontrasting
confidence: 57%
“…Mild perivascular dermal infiltrate has been reported at the leading edge of LCAI 16,17 . The brisk, deep dermal and lobular lymphocytic infiltrate seen in our case exceeds that presented in other reports.…”
Section: Discussioncontrasting
confidence: 57%
“…In 1982 Giatn et al (2) and Lee et al (3) described the first cases outside of Japan in a Chinese boy and eight Koreans, respectively. Fewer than 100 cases of LCAI have been reported lo date.…”
mentioning
confidence: 98%
“…Lipodystrophia centrifugalis abdominalis infanlilis (LCAI) is a rare disorder first de.scribed by Imamura et al (1) in 1971. In 1982 Giatn et al (2) and Lee et al (3) described the first cases outside of Japan in a Chinese boy and eight Koreans, respectively. Fewer than 100 cases of LCAI have been reported lo date.…”
mentioning
confidence: 99%
“…The mechanism of LCAI also remains unknown, though several hypotheses have been presented that the degeneration of fatty tissue is the primary change, and the inflammatory change observed in the periphery is a reactive change [3, 6]. In the degenerating subcutaneous fatty tissue, positive staining for HLA-DR, bcl-2, Fas and p53 in mononuclear cells were observed.…”
Section: Discussionmentioning
confidence: 99%
“…The differential diagnosis includes atrophoderma of Pasini-Pierini, morphea, lipogranulomatosis subcutanea, subcutaneous fat necrosis of the newborn and lupus erythematosus profundus [1, 3]. All of these diseases were excluded by clinical and histological findings.…”
Section: Discussionmentioning
confidence: 99%