Lipogranulomatous conjunctivitis: clinical findings from 21 eyes in 13 cats

Abstract

Histologic features of tissues excised from surgically treated cases were consistent with a previous report of lipogranulomatous conjunctivitis and with descriptions of chalazia. A possible role of actinic radiation in the etiopathogenesis of lesions is discussed.

A case of lipogranulomatous conjunctivitis in a horse

“…Follow‐up after surgical excision of the lesions was excellent for months, with good ocular comfort; however, the emergence of new conjunctival nodules was observed 3 years later. In eight surgically treated cats, no signs of significant recurrence were observed during the 4‐ to 21‐month follow‐up period 1 . However, the possibility of late recurrence cannot be excluded.…”

“…1,2 The presence of large droplets of presumed free lipid in the conjunctival lamina propria and granulomatous inflammation are the most consistent histopathological findings. 1,2 In cats, damage caused by solar ultraviolet radiation has been suspected in the etiopathogenesis of this disease. 1 Here, we report a case of bilateral chronic conjunctivitis in a horse that shared clinical and histopathological features with those previously described in cats.…”

“…1,2 In cats, damage caused by solar ultraviolet radiation has been suspected in the etiopathogenesis of this disease. 1 Here, we report a case of bilateral chronic conjunctivitis in a horse that shared clinical and histopathological features with those previously described in cats. To our knowledge, this is the first report of lipogranulomatous conjunctivitis in a horse.…”

Staphyloma in a cat

“…The most likely differential diagnoses for a subconjunctival mass include staphyloma, emphysema, subconjunctival hemorrhage and foreign body 1–4 . Less likely differential diagnoses include inflammation (eosinophilic, fibrous histiocytoma and lipogranulomatous), infection (cryptococcosis, blastomycosis, and histoplasmosis), neoplastia (osteoma, lymphosarcoma, squamous cell carcinoma, fibrosarcoma, papilloma, adenomas, adenocarcinomas, hemangioma, hemangiosarcoma and limbal or conjunctival melanoma), or a dermoid 1,5–14 …”

“…[1][2][3][4] Less likely differential diagnoses include inflammation (eosinophilic, fibrous histiocytoma and lipogranulomatous), infection (cryptococcosis, blastomycosis, and histoplasmosis), neoplastia (osteoma, lymphosarcoma, squamous cell carcinoma, fibrosarcoma, papilloma, adenomas, adenocarcinomas, hemangioma, hemangiosarcoma and limbal or conjunctival melanoma), or a dermoid. 1,[5][6][7][8][9][10][11][12][13][14] The differential diagnoses for a feline cataract include congenital (alone or associated with multiple ocular anomalies and Chediak-Higashi syndrome), trauma, hereditary, or secondary to anterior uveitis. [15][16][17][18][19][20][21][22] Less likely differentials include metabolic (diabetes mellitus and nutritional or primary hyperparathyroidism), nutritional (potentially related to milk replacer deficient in arginine), and iatrogenic causes (chronic topical dexamethasone).…”