Lipoleiomyoma of the Uterine Cervix: A Case Report

Abstract

ÖZ

Lipoleiomyomas of the Uterine Cervix: A New Series including the First Recurrent Case and the First Systematic Literature Review

“…The majority of cases were diagnosed in Asia (27/44, 61%), followed by North America (9/44, 20%), Europe (6/44, 14%), and Africa (2/44, 5%), while no cases were reported in other continents. The majority of cases were described in India (13/44, 30%) [19][20][21][22]25,27,[30][31][32][33][34]36,39], the United States (9/44, 21%) [16,28,38], and Turkey (8/44, 18%) [15,17,18,23]. According to our review, cervical LLMs were not described in North America, except for the United States, while the two African cases were reported in North Africa (one in Egypt and one in Morocco) [29,35].…”

“…The age range of the reported 31 patients was 35-74 years (mean: 46.5 years; median: 43 years). Ten women (32%) were clearly or probably postmenopausal [20,22,23,28,31,37,[40][41][42], while 21/29 (68%) cases were pre-or peri-menopausal [18,19,21,[24][25][26][27]29,30,[32][33][34][35][36]38,39]. Information about parity was available in only 16 (52%) cases [18,19,21,25,28,29,31-33, 35,36,38,41,42]; 15/16 (94%) women were multiparous [18,19,21,25,28,29,[31][32][33]35,36,41,42], while only 1 (6%) of 16 patients had only one child [38]; no woman was clearly nulliparous.…”

“…The most frequent symptoms were vaginal bleeding (11/31, 36%) [19][20][21]26,29,30,35,36,39,41] and pelvic/abdominal pain (10/31, 32%) [19][20][21]23,[29][30][31][32][33]37], followed by urinary disturbances (6/31, 19%) (1 not otherwise specified [22]; 2 stress incontinence [25]; 1 difficulty in micturition [30]; 2 hesitancy/difficulties in passing urine [19,34]). Occasionally, patients experienced low abdominal distension (three cases, including one due to a concomitant ovarian tumor) [37,38,40], vaginal discomfort (one case) [32], inguinal pain (one case) [18], or dyspepsia (one case) [33] at presentation.…”

“…The time interval between the onset of symptoms and the clinical exam ranged from 1 week to 10 months. Thirteen patients (42%) complained of one symptom [18,22,23,25,26,31,[34][35][36][37][39][40][41], six women (19%) experienced two symptoms [20,21,29,32,33], and two patients (6%) presented three symptoms [19,30]. In nine (29%) cases, data about clinical symptoms were unavailable [24,27,28,38,40], while one (3%) patient was clearly asymptomatic [42].…”

“…Other findings included synchronous leiomyomas of the uterine body (n = 10, 32%) [22,23,25,27,28,30,34,40], left ovarian mucinous cystadenoma (n = 1, 3%) [40], right paratubal serous cystadenoma (n = 1, 3%), 2.1-cm adult granulosa cell tumor of the right ovary (n = 1, 3%) [38], 8-cm Sertoli cell tumor of the right ovary (pT1a) [42], and cervical H-SIL (n = 1, 3%) [40]. Pap smears were performed in three other cases (10%) (including our first case), always resulting in a negative result [19,42].…”