Lipomas intracranianos: achados de imagem/ Intracranial lipomas: imaging findings

Abstract

Os lipomas intracranianos são tumores benignos raros, que consistem em malformações congênitas que representam menos de 0,5% de todos os tumores intracranianos. Podem ocorrer em qualquer lugar do encéfalo, e desenvolvem-se frequentemente na região da linha média supratentorial. A fisiopatologia aceita é que os lipomas consistem do resultado de uma diferenciação anormal da meninge primitiva. Na maioria das vezes são assintomáticos e encontrados incidentalmente durante autópsias ou investigações neurorradiológicas para outras condições . Em relação aos exames de imagem, os achados da tomografia computadorizada (TC) e da ressonância magnética (RM) são característicos da lesão, portanto, a confirmação da biópsia não é necessária para o diagnóstico.

Pericallosal-Interhemispheric Lipoma Associated With Bilateral Ventricular Choroid Plexus Lipomas With Corpus Callosal Dysgenesis: Case Report

“…Usually, they are either midline or adjacent to midline structures. PCL account for 50% of all intracranial lipomas [2,3,4,5] .…”

“…Its diagnoses have become possible thanks to advances in neuroradiological examination modalities with high-resolution imaging. Computed tomography (CT) and magnetic resonance imaging (MRI) findings are capable of accurately characterizing the fatty nature of the lesion, allowing for the diagnosis of intracranial lipomas with a high degree of reliability without biopsy confirmation [4,14] .…”

“…These lesions are rare, benign and consist in a slow growing congenital anomalous maldevelopment that accounts of 0.1 -0.5% of all primary brain tumor. PCL account for 50% of all intracranial lipomas [2,3,4,5] . Hassan describes that the pathogenesis of a pericallosal lipoma is considered to be the result of an abnormal resorption of the primitive meninges [6] .…”

“…About half of PCL cases are asymptomatic and they are conservatively managed [10] . An increase in the recent diagnosis of intracranial lipomas is observed thanks to advances in neuroradiological examination modalities with high-resolution imaging [4,14] . CT and MR findings of intracranial lipomas are very characteristic [3,15,16,17] .…”