Abstract:Background: Spinal dysraphism, one of the most common birth defects, has been estimated to occur annually in more than 320,000 infants worldwide. Lipomyelomeningocele (LipoMMC) is a closed neural tube defect in which the surface lipomatous tissue is attached to the spinal cord. LipoMMC results from premature disjunction of the epithelial ectoderm from the neural ectoderm at a gestational age of 18–28 postovulatory days.Both genetic and environmental factors are suggested to have important roles in the occurren… Show more
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