Lipophilic extracts of the thermophilic cyanobacterium Leptolyngbya sp. and chlorophyte Graesiella sp. and their potential use as food and anticancer agents

Gara-Ali, Marwa; Zili, Fatma; Hosni, Karim; Ouada, Hatem Ben; Ben-Mahrez, Kamel

doi:10.1016/j.algal.2021.102511

Cited by 12 publications

(1 citation statement)

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“…Despite its high importance in production of alternative natural products with biotechnological and pharmaceutical applications and the ability of their biomass to be used as food products or dietary supplement the commercial scale production and microalgae market is still restricted to only few strains (Kim et al, 2015). The organic solvent extracts of marine cyanobacteria showed efficient effects against different species of microorganisms and proved to have cytotoxic influence against some tumor cell lines (Martins et al, 2008;Gara-Ali et al, 2021). Cyanobacteria found to contain polar and nonpolar lipids which have a role in algal protection against extreme environmental conditions such as high salinity, -59 -desiccation and high light intensity (Ananya and Kamal 2016).…”

Section: Introductionmentioning

confidence: 99%

Identifying of the bioactive compounds from two aquatic cyanobacteria, Leptolyngbya sp. and Desertifilum sp., with antioxidant and antimicrobial activities

Shawer

El-Gamal

Sabae

et al. 2022

Egyptian Journal of Phycology

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Cyanobacterial metabolites have gained a great attention during the last few decades, as they are a potential source for bioactive compounds. In the present study the total phenolic and flavonoid compounds in the biomass of Leptolyngbya sp. Q1 (MZ504747) and Desertifilum sp. Q2 (MZ504748) were estimated and their methanolic extracts were screened for their free radical scavenging activity against 2,2-diphenyl-1picrylhydrazyl (DPPH) and antimicrobial activity (well diffusion method) against different Gram-positive, Gram-negative bacteria in addition to Candida albicans. The results showed that Leptolyngbya sp. had higher total phenolic compounds content (8.89± 0.89 mg GAE/g DW) and total flavonoid content (1.72± 0.01 mg QE/g DW) compared to those recorded in Desertifilum sp. Both extracts were detected to have antioxidant activity against DPPH free radicals, and the IC50 values were 2.18 and 2.85 mg/ml for Leptolyngbya sp. and Desertifilum sp., respectively. Also, Leptolyngbya sp. extract was determined to have higher antimicrobial activity against tested microorganisms compared to Desertifilum sp. extract. Finally, the GC-MS profile for both extracts indicated the presence of phenolic compounds, saturated and unsaturated fatty acids such as 3-Allyl-2methoxyphenol, Tetradecanoic acid (Myristic acid), n-Hexadecanoic acid (Palmitic acid), Phytol, Linoleic acid, Linolenic acid, Palmitoleic acid, cis-Vaccenic acid and other bioactive compounds of well-known pharmaceutical and industrial importance.

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Section: Introductionmentioning

confidence: 99%