Lipoprotein(a) and coronary artery calcium in comparison with other lipid biomarkers: The multi-ethnic study of atherosclerosis

Jackson, Candace L.; Garg, Parveen K.; Guan, Weihua; Tsai, Michael Y.; Criqui, Michael H.; Tsimikas, Sotirios; Bhatia, Harpreet

doi:10.1016/j.jacl.2023.06.002

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Lp(a) As a Risk Enhancing Factor For Ascvd1

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2024

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Cited by 8 publications

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“…One analysis from the Heinz Nixdorf Recall study suggested Lp(a) to be a causal risk factor for CAC by demonstrating a significant association between a single nucleotide polymorphism at the Lp(a) locus and CAC [30] . However, more recent data from MESA demonstrated that Lp(a) was not associated with baseline CAC volume or density and was only modestly associated with volume progression [31] . Apart from CAC, advanced plaque composition assessment by coronary computed tomography angiography (CCTA) has shown that among patients with advanced stable CAD, Lp(a) is associated with accelerated progression of low-attenuation plaque (a quantitative marker of necrotic core and high risk plaque) [32] .…”

Section: Lp(a) As a Risk Enhancing Factor For Ascvdmentioning

confidence: 94%