Liposarcoma of the spermatic cord: A case report and review of literature

Scrotal liposarcoma: Case report of a rare extratesticular mass

“…8 Scrotal liposarcomas are a very rare extratesticular mass derived embryonically from mesodermal tissue but can also arise from the testicular tunica or epididymis. 5 The most commonly held belief is that paratesticular liposarcomas arise from the spermatic cord tissue, however other research has stated the possibility of occurrence through malignant degeneration of a pre-existing lipoma. 5 The World Health Organisation has grouped liposarcomas histologically into five different categories: atypical lipomatous tumour/well differentiated, dedifferentiated, myxoid, pleomorphic and mixed-type liposarcoma.…”

“…5 The most commonly held belief is that paratesticular liposarcomas arise from the spermatic cord tissue, however other research has stated the possibility of occurrence through malignant degeneration of a pre-existing lipoma. 5 The World Health Organisation has grouped liposarcomas histologically into five different categories: atypical lipomatous tumour/well differentiated, dedifferentiated, myxoid, pleomorphic and mixed-type liposarcoma. 1,9 Dedifferentiated and pleomorphic liposarcomas are generally regarded as high-grade, aggressive tumours with metastatic F I G U R E 2 Scrotal ultrasound demonstrating the relationship of an inhomogeneous, well-defined, ovoid, vascular mass (*) to the left inguinal canal and testicle F I G U R E 3 Computed tomography demonstrating a well-circumscribed low-density lesion (*) within the left hemi-scrotum superior to the testicle potential.…”

“…Radical surgical excision of the lesion with orchidectomy is usually the standard approach. 2,4,5,13 In cases with high-grade lesions, those with lymphatic metastasis, inadequate surgical margins or recurrence, radiation therapy is also recommended. 5,13 The benefit of chemotherapy is not well-documented in the literature.…”

“…[1][2][3] The prevalence of paratesticular liposarcomas in the literature varies between 100 and 327 reported cases worldwide. [3][4][5][6][7] It commonly presents as a slow growing mass in the inguinal canal or scrotum, often leading to misdiagnosis as a testicular or epididymal tumour or inguinal hernia. 2 In addition, due to the rarity of this lesion, treatment and prognosis of the disease are largely based on case reports.…”

Laparoscopic‐assisted surgery for liposarcoma of the spermatic cord extending to the retroperitoneal cavity through the internal inguinal ring

“…LSC is a rare soft tissue malignant neoplasm derived from fat cells in the spermatic cord. Recently, 327 cases of LSC have been reported . Liposarcoma (46%) is the most common histologic type of malignant SCT, followed by leiomyosarcoma (20%), histiocytoma (13%), and rhabdomyosarcoma (9%) .…”