“…AmB is therefore ineffective in treating invasive aspergillosis caused by A. terreus ( Blum et al., 2013a ). Additionally, AmB has harmful side effects including glomerular filtration rate reduction, hypokalemia, hepatotoxicity, and cell toxicity ( Ramu et al., 2021 ). Clinical trials have indicated that AmB treatment has a significant failure rate (80 %–90 %) against invasive aspergillosis induced by A. terreus ( Walsh et al., 2003 ).…”