Liposomal incorporation of Artemisia arborescens L. essential oil and in vitro antiviral activity

Sinico, Chiara; Logu, Alessandro De; Lai, Francesco; Valenti, Donatella; Manconi, Maria; Loy, Giuseppe; Bonsignore, Leonardo; Fadda, Anna Maria

doi:10.1016/j.ejpb.2004.06.005

Cited by 186 publications

(79 citation statements)

References 20 publications

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“…The studies carried out on this species were mainly concerned about its phytochemical characteristics [1,29,30,32,33,39], but other aspects have been also considered, such as its genomics [19], its antiviral [43], antioxidant [11], anti-mycoplasmal [3] and allelochemical properties [14]. However, to our knowledge, no studies have been carried out on the antibacterial properties of EOs of this species.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

et al. 2010

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This study was undertaken to characterize the essential oil (EO) of Artemisia arborescens growing wild in Sicily. EO, extracted by steam distillation, was examined for its chemical composition and for its capability to inhibit some food-borne pathogen bacteria. A total of 43 compounds (13 monoterpene hydrocarbons, 14 oxygenated monoterpenes, 10 sesquiterpene hydrocarbons, three oxygenated sesquiterpenes and less amount of other three compounds), which account 93.73% of the total oil, were identified by gas chromatography and gas chromatography-mass spectrometry. Oxygenated monoterpenes (57.32%) constituted the main fraction, with b-thujone as the main compound (45.04%), followed by the sesquiterpene hydrocarbon chamazulene (22.71%). Undiluted EO showed a large inhibition spectrum against strains of Listeria monocytogenes (34 out of 44), whilst it was ineffective against enterobacteria and salmonellas. The minimum inhibition concentration (MIC) was evaluated for the two most sensitive strains (L. monocytogenes 186 and 7BO) at two cellular concentrations (10 6 and 10 7 CFU ml -1 ). The lowest MIC (0.625 ll ml -1 , dilution of oil with acetone) was found for strain L. monocytogenes 186 at 10 6 CFU ml -1 .

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Section: Introductionmentioning

confidence: 99%

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

et al. 2010

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“…Liposomes can encapsulate hydrophilic compounds in the aqueous internal cavity, and hydrophobic substances can be dissolved into the membrane. Because of their ease of biodegradation and their similarity to cell biomebranes, they are less toxic than polymer or other wall materials and they are excellent carrier systems for a variety of applications, and in particular for essential oils [37,38].…”

Section: Coating Materialsmentioning

confidence: 99%

“…Other techniques such as annularjet or spinning-jet drying can be used to produce particles loaded with liquids such as essential oils. Table 3 shows some applications of these techniques for essential oil formulation [34][35][36][37][38][61][62][63][64][65][66][67][68][69][70][71][72][73][74][75].…”

Section: Other Techniquesmentioning

confidence: 99%

“…Freeze drying appears as one of the most suitable methods for dehydration of almost all heat-sensitive materials and aromas, due to the lower operating temperatures, slow drying rate and to the use of vacuum. This technique has also been used to encapsulate essentials oils [37,61].…”

Section: Other Techniquesmentioning

confidence: 99%

“…Finally, solidification of the coating is achieved by thermal, cross-linking or desolventization techniques. Another closely related technique is the organic phase separation, which can be considered as a reversed simple coacervation: a polymer phase separates and deposits on a core that is suspended in an organic solvent rather than in water Several essentials oils were encapsulated by coacervation employing gelatine [37,62], proteins [63] and other polymers [64]. …”

Section: Other Techniquesmentioning

confidence: 99%

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Encapsulation and Co-Precipitation Processes with Supercritical Fluids: Applications with Essential Oils

Martín¹,

Varona²,

Navarrete³

et al. 2010

TOCENGJ

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Essential oils have important commercial applications as preservatives and flavours, and more recently as natural antimicrobial agents. These applications require a suitable formulation constituted by biodegradable compounds that protect the essential oil from degradation and evaporation at the same time that allows for a sustained release. Microcapsules of biopolymers loaded with essential oils meet these requirements. Such microcapsules can be prepared with different processes such as spray-drying, freeze-drying and coacervation, and supercritical fluids are an advantageous medium for this purpose. Some supercritical fluid-based precipitation processes have already been applied to produce these microcapsules. Amongst them, the results obtained with Particles from Gas Saturated Solutions (PGSS), PGSS-drying and Concentrated Powder Form (CPF) processes are particularly promising. Recent developments in the preparation of formulations with supercritical fluids include the preparation of liposomes and micelles, which can be suitable carriers for essential oils.

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Chemistry and Bioactivity of Essential Oils

Carson

Hammer

2010

Lipids and Essential Oils as Antimicrobial Agents

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Liposomal incorporation of Artemisia arborescens L. essential oil and in vitro antiviral activity

Cited by 186 publications

References 20 publications

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

Encapsulation and Co-Precipitation Processes with Supercritical Fluids: Applications with Essential Oils

Chemistry and Bioactivity of Essential Oils

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