Liposomes for microcompartmentation of enzymes and their influence on catalytic activity

Wichmann, Carolin; Naumann, P; Spangenberg, Oliver; Konrad, Manfred; Mayer, Frank; Hoppert, Michael

doi:10.1016/j.bbrc.2003.09.128

Cited by 17 publications

(8 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As descried above, water at the interface of a hydrophilic thin film forms an exclusion zone which has a higher density than ordinary water. A similar phenomenon was observed for a hydrated hydrophilic ceramic powder, and water turns into a threedimensional structure composed of high density water and low density water [14]. A report outlines a study of antioxydant properties of this "structured" water and on its effect on cell bioactivities.…”

Section: Antioxydant Water?supporting

confidence: 59%

Water and Human Health - Insights, Concepts, Hopes, Dreams

2020

Jpn J Med

View full text Add to dashboard Cite

Water is essential for life. Its importance for the physical health of the human body is common knowledge. This circumstance was and is one of the major reasons for the studies of the properties of water. During the last two decades, significant progress was made by these studies, and surprising results were reported. New insights were obtained by the discovery of a fourth phase of water (EZ water, high density water and low density water), by studies of the states of water in the biological cell and of so far unknown consequences of these findings, by development of alternative water models (dense water actually heavily discussed) and, as a major aspect, by application of concepts for investigations of the role of water as antioxydant. In this context, an ongoing discussion of hopes and dreams regarding physical and mental health and longevity is on the way.

show abstract

Section: Antioxydant Water?supporting

confidence: 59%

Water and Human Health - Insights, Concepts, Hopes, Dreams

2020

Jpn J Med

View full text Add to dashboard Cite

show abstract

“…The exact conformation of transertion hyperstructures is unknown but could be very important in bacterial cell physiology if, as proposed, interactions between hyperstructures were to be the primary determinants of the phenotype (Norris et al, 2007a). For example, interactions based on the condensation and decondensation of ions (Manning, 2007) might enable transertion hyperstructures containing membrane domains and/or linear assemblies of macromolecules to drive the cell cycle (Norris and Amar, 2012) whilst the kinetics of the reactions in the vicinity of a membrane domains are likely to be different from elsewhere, possibly due to the structuring of water (Wichmann et al, 2003). …”

Section: Discussionmentioning

confidence: 99%

The membrane: transertion as an organizing principle in membrane heterogeneity

et al. 2015

View full text Add to dashboard Cite

The bacterial membrane exhibits a significantly heterogeneous distribution of lipids and proteins. This heterogeneity results mainly from lipid–lipid, protein–protein, and lipid–protein associations which are orchestrated by the coupled transcription, translation and insertion of nascent proteins into and through membrane (transertion). Transertion is central not only to the individual assembly and disassembly of large physically linked groups of macromolecules (alias hyperstructures) but also to the interactions between these hyperstructures. We review here these interactions in the context of the processes in Bacillus subtilis and Escherichia coli of nutrient sensing, membrane synthesis, cytoskeletal dynamics, DNA replication, chromosome segregation, and cell division.

show abstract

“…Under the conditions causing conformational change of the membrane-linked proteins, hydrophobic interaction is induced between the proteins and the host membranes [10]. Wichmann et al [11] reported that anchoring the ␣-amylase and guanylase kinase to the surface of liposomes definitely alter the enzyme thermal stabilities. The enzyme molecules conjugated with liposomes therefore possess the peculiar stability and catalytic function which are potentially useful not only in the biomedical field but also in developing functional biocatalysts for bioproduction processes.…”

Section: Introductionmentioning

confidence: 98%