Liposomes for the transport of an impermeable fluorescent dye into muscle fibers

Preparation of [5‐125I]iodoacetamidoethyl aminonaphthalene‐1‐sulfonic acid in liposomes

“…The transport of an impermeable dye, 5-(iodoacetamidoethyl) aminonaphthalene-1-sulfonic acid (IAEDANS) into muscle fibers with positively charged liposomes was accomplished, and it was demonstrated that the dye, after uptake by the fibers, was bound to intracellular actin (2). Furthermore, these liposomes were capable of delivering IAEDANS to infarcted cells in the guinea pig myocardium after experimental coronary after one hour.…”