Liposomes loaded with Salvia triloba and Rosmarinus officinalis essential oils: In vitro assessment of antioxidant, antiinflammatory and antibacterial activities

Risaliti, Laura; Kehagia, Aspasia; Daoultzi, E; Lazari, Diamanto; Bergonzi, Maria Camilla; Vergkizi-Nikolakaki, Susan; Hadjipavlou‐Litina, Dimitra; Bilia, Anna Rita

doi:10.1016/j.jddst.2019.03.034

Cited by 84 publications

(51 citation statements)

References 16 publications

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“…[401] As per as loading EOs on nanocapsules with biologically active and recognized as safe for human health metal elements (such as copper). [402] The delivery of EOs could be optimized also by their encapsulation on nanostructured lipid carriers prepared by phase inversion temperature and high pressure homogenization methods, [403] on liposomes prepared using the film hydration method [404] or on nanocochleates based on phosphatidylcholine, cholesterol and calcium ions [405] with interesting increase of their effectiveness and stability. Nanoarchaeosomes made of soybean phosphatidylcholine, polysorbate 80 and total polar archaeolipids extracted from archaebacterial Halorubrum tebenquichense and loaded with thyme EO were successfully tested for their anti MRSA biofilm activity opening new ways for the exploitation of these kind of nanovesicles loaded with EOs.…”

Section: Cultural Heritage Preservationmentioning

confidence: 99%

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Napoli

Siracusa

Ruberto

2020

Chemistry & Biodiversity

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Lamiaceae is one of the largest families of flowering plants comprising about 250 genera and over 7,000 species. Most of the plants of this family are aromatic and therefore important source of essential oils. Lamiaceae are widely used as culinary herbs and reported as medicinal plants in several folk traditions. In the Mediterranean area oregano, sage, rosemary, thyme and lavender stand out for geographical diffusion and variety of uses. The aim of this review is to provide recent data dealing with the phytochemical and pharmacological studies, and the more recent applications of the essential oils and the non‐volatile phytocomplexes. This literature survey suggests how the deeper understanding of biomolecular processes in the health and food sectors as per as pest control bioremediation of cultural heritage, or interaction with human microbiome, fields, leads to the rediscovery and new potential applications of well‐known plants.

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Section: Cultural Heritage Preservationmentioning

confidence: 99%

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Napoli

Siracusa

Ruberto

2020

Chemistry & Biodiversity

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“…Entretanto, apresenta limitações consideráveis no que se refere às suas propriedades físico-químicas, pois são quimicamente instáveis na presença de ar, luz, umidade e altas temperaturas (Cui et al, 2015 originalmente da região do mediterrâneo ocidental, é bastante utilizado na medicina e na culinária. O seu óleo é composto principalmente de eucaliptol e cânfora e apresenta várias propriedades, dentre elas, a atividade antimicrobiana (Risaliti et al, 2019 [77]…”

Section: Resultados E Discussõesunclassified

Ciências Da Saúde E Suas Contribuições Sociais

Rocha¹,

Cunha²,

Da³

2020

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RESUMO O escopo deste artigo é analisar como é estabelecida a relação entre a Síndrome de Fibromialgia e a depressão, vista a alta demanda de pacientes acometidos pelas enfermidades. Para nos fundamentar teoricamente, partimos da concepção de Mello-Filho et al (2010) sobre fibromialgia, Dalgalarrondo (2008) sobre depressão, Lipp (2001) e Homann et al (2012) para elucidar conceitos de estresse, todos fundantes para o processo de sistematização de informações e escrita deste trabalho. Para realizar a presente análise, partimos da metodologia de revisão bibliográfica integrativa, a partir da qual analisamos 4 artigos científicos coletados das plataformas digitais: Google Scholar, SciELO e PePsic. Para isto, partimos da seguinte pergunta norteadora: "qual a relação entre a fibromialgia e a depressão denotada nas pesquisas mais recentes?" Enquanto resultados, pudemos perceber a escassez de pesquisas recentes na área, principalmente na Psicologia, além de todas as pesquisas serem realizadas com o público feminino, por esse ser mais afetado pelo transtorno fibromiálgico. Além disso, é perceptível uma forma reducionista de lançar luz sobre a depressão, como se esta fosse apenas um sintoma da fibromialgia que pode ser desenvolvido ou não, negando o caráter individual da doença. Não se verificou uma abordagem sobre o ponto de vista psicopatológico e nem mesmo uma causa bem definida para o surgimento da doença em questão. A partir disso, pôde-se concluir a necessidade de uma maior investigação sobre os casos de fibromialgia e seu surgimento, qual a sua relação com as condições socioeconômicas, educacionais e de gênero. Além disso, é necessária uma fomentação nas pesquisas científicas acerca do tema.

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“…The release of MEO from MEO-GS was evaluated by the dialysis bag method [29,30], using Spectra/Por ® regenerated cellulose membranes with 3.5 KDa MWCO), by Repligen Europe B.V. (Breda, The Netherlands), and it was compared to the release from a DMSO solution of MEO, at the same concentration of essential oil as used to prepared glycerosomes (10 mg/mL). The experiment was carried out with 1 mL of sample, magnetically stirred in 200 mL of PBS, used as release medium.…”

Section: In Vitro Releasementioning

confidence: 99%

Glycerosome of Melissa officinalis L. Essential Oil for Effective Anti-HSV Type 1

et al. 2020

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Essential oils are complex mixtures of strongly active compounds, very volatile and sensitive to light, oxygen, moisture and temperature. Loading inside nanocarriers can be a strategy to increase their stability and successfully use them in therapy. In the present study, a commercial Melissa officinalis L. (Lamiaceae) essential oil (MEO) was analyzed by gas chromatography-mass spectrometry, loaded inside glycerosomes (MEO-GS) and evaluated for its anti-herpetic activity against HSV type 1. MEO-GS analyses were prepared by the thin layer evaporation method and they were characterized by light scattering techniques, determining average diameter, polydispersity index and ζ-potential. By transmission electron microscopy, MEO-GS appeared as small nano-sized vesicles with a spherical shape. MEO encapsulation efficiency inside glycerosomes, in terms of citral and β-caryophyllene, was found to be ca. 63% and 76% respectively, and MEO release from glycerosomes, performed by dialysis bag method, resulted in less than 10% within 24h. In addition, MEO-GS had high chemical and physical stability during 4 months of storage. Finally, MEO-GS were very active in inhibiting HSV type 1 infection of mammalian cells in vitro, without producing cytotoxic effects. Thus, MEO-GS could be a promising tool in order to provide a suitable anti-herpetic formulation.

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Liposomes loaded with Salvia triloba and Rosmarinus officinalis essential oils: In vitro assessment of antioxidant, antiinflammatory and antibacterial activities

Cited by 84 publications

References 16 publications

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Ciências Da Saúde E Suas Contribuições Sociais

Glycerosome of Melissa officinalis L. Essential Oil for Effective Anti-HSV Type 1

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