Liposomes – the potential drug carriers

Abstract

Liposomes have been widely investigated since 1970 as drug carriers for improving the delivery of therapeutic agents to specific sites in the body. As a result, numerous improvements have been made, thus making this technology potentially useful for the treatment of certain diseases in the clinics. The success of liposomes as drug carriers has been reflected in a number of liposome-based formulations, which are commercially available or are currently undergoing clinical trials. This review is focused on the various aspects of liposomes starting from the evolution and the current research including the detailed summary such as classification, methods of preparation, characterization and the potential use of liposomes in the treatment of various diseases and the various sites to which these are targeted.Liposomes have covered predominantly medical, albeit some non-medical areas like bioreactor, catalysts, cosmeticsand ecology. However, their predominance in drug delivery and targeting has enabled them to be used astherapeutics tool in fields like tumor targeting, gene and antisense therapy etc.

Formulation of Liposome using Sappan wood (Caesalpinia Sappan L.) Ethyl acetate Fraction as an activate compound

“…Some of the existing drug delivery systems are nio some, resealed erythrocytes, pharmacosomes, and liposome. Among the drug delivery systems, liposome is one of the fastest growths 1,2,3 .…”