Since the early beginnings of the space age in the 1950s, solar cells have been considered as the primary choice for long term electrical power generation of satellites and space systems. This is mainly due to their high power/mass ratio and the good scalability of solar modules according to the power requirements of a space mission. During the last decades, detailed solar cell material studies including the non-trivial interaction with high-energy space particles have led to continuous and significant improvements in device efficiency. This allowed the powering of advanced space systems like the International Space Station, rovers on the Martian surface as well as satellites which have helped to understand the universe and our planet. It is noteworthy that in addition to their success in space, these photovoltaic technologies have also broken ground for the application of photovoltaic systems in terrestrial systems. This paper discusses the development of space solar cells, gives insight into related experiments like the analysis of the interaction with space particles and provides an overview on challenges and requirements for future space missions.