Earthquake is a natural phenomenon occurring with all unpredictability. During the earthquake, ground motions occur in a random fashion, both horizontally and vertically, in all directions radiating from focal point. These cause structures to vibrate and induce inertia forces on them Earthquake engineering is a versatile branch of engineering that designs and analysis structure, such as building and bridges, with earthquakes in mind. Its overall aim is to make such structures more resistant to earthquakes. This time making comparative study about vulnerability analysis of structure which built on sand i.e. desert, soft soil. I will design Seismic analysis of structure which built on sand and soft soil by using the software ETABS and The IS code assigned a zone factor of 0.36 for zone 5. Structural designers use this element for earthquake resistant design of structures in zone 5. This region throughout structure according to Indian IS code 1893:2002 and for wind load IS 875:1987.