Liquid chromatographic method with ultraviolet absorbance detection for measurement of levamisole in chicken tissues, eggs and plasma

Electromembrane extraction of levamisole from human biological fluids

“…Therefore, the proposed method can reduce risk of working with biological fluids and loss of sample during treatment steps. LLE has disadvantages such as consumption of large amount of organic solvents and large secondary wastes, which are toxic and harmful for environment and is a time‐consuming procedure especially when solvent evaporation 32 was used.…”

“…Various techniques have been used for determination of levamisole in biological fluids up to now. They include membrane ion‐selective electrodes 23, gas chromatography with nitrogen–phosphorus detection (GC‐NPD) 24, 25, and flame ionization detection (GC‐FID) 26, and liquid chromatography with ultraviolet (LC‐UV) detection 27, and mass spectrometry detection (LC‐MS) 28, 29. In all of the mentioned techniques, sample preparation is a critical problem especially in complicated matrices.…”

Potentiometric Membrane Sensors for Levamisole Determination

“…Various techniques have been used for the determination of levamisole in biological fluids. They include gas chromatography with nitrogenphosphorus detection (GC-NPD) 2 and flame ionization (GC-FID) [3] and liquid chromatography (LC) with ultraviolet (UV) detection [4][5][6][7] . Several methods have been developed for levamisole quantification such as polarography 8 , by a turbidimetric method and flow-injection analysis 9 .…”

Development of RP-HPLC Method for the Simultaneous Quantitation of Levamisole and Albendazole: Application to Assay Validation

“…Some of the methods for determination of levamisole, along with some antihelminthics in various biological samples by HPLC, have been developed, including determination of the anthelmintic levamisole in plasma and gastrointestinal fluids by high-performance liquid chromatography by Marriner S et al [ 18 ], determination of levamisole by HPLC in plasma samples in the presence of heparin and pentobarbital by Garcia JJ et al [ 19 ], determination of levamisole and thiabendazole in meat by de Bukanski BW et al [ 20 ], quantitation of levamisole in plasma using high-performance liquid chromatography by Vandamme TF et al [ 21 ], solid-phase extraction and HPLC determination of levamisole hydrochloride in sheep plasma by Du Preez JL et al [ 22 ], determination of levamisole in animal tissues using liquid chromatography by E. Dreassi et al [ 23 ], quantitative chromatographic determination of several benzimidazole anthelmintic molecules in parasite material by Mottier L et al [ 24 ], liquid chromatographic method with ultraviolet absorbance detection for measurement of levamisole in chicken tissues, eggs, and plasma done by El-Kholy H et al [ 25 ], quantitative determination of albendazole metabolites in sheep spermatozoa and seminal plasma by Batzias GC et al [ 26 ], a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma by Wu Z et al [ 27 ], HPLC assay of levamisole and abamectin in sheep plasma for application to pharmacokinetic studies by Sari P et al [ 28 ], determination of levamisole in sheep muscle tissue by Tyrpenou AE et al [ 29 ], and investigation of the persistence of levamisole and oxyclozanide in milk and fate in cheese by M. Whelan et al [ 30 ]. Determination of levamisole with other anthelmintic agents in pharmaceuticals including veterinary preparations by HPLC includes high-performance liquid chromatography method for the analysis of several anthelmintics in veterinary formulations by E. C. Van-Tonder et al [ 31 ], simultaneous determination of levamisole hydrochloride and mebendazole in tablets by R. Raman et al [ 32 ], separation and determination of the process related impurities of mebendazole, fenbendazole, and albendazole in bulk drugs by Gomes AR et al [ 33 ], simultaneous determination of levamisole and abamectin in liquid formulations by P. Sari et al [ 34 ], simultaneous estimation of levamisole, mebendazole, and albendazole in pharmaceutical products by Kullai Reddy Ulavapalli et al [ 35 ], method for determination of levamisole in bulk and dosage form by Ravisankar P et al [ 36 ], enantioseparation of tetramisole by capillary electrophoresis and high-performance liquid chromatography and application of these techniques to enantiomeric purity determination of a veterinary drug formulation of L-levamisole done by B. Chankvetadze et al [ 37 ], UPLC method for the determination of albendazole residues pharmaceutical manufacturing equipment surfaces by R. S. Chandan et al [ 38 ], and HPTLC method for simultaneous estimation of levamisole hydrochloride and oxyclozanide in it...…”