Liquid-crystal intraocular adaptive lens with wireless control

Simonov, A. N.; Vdovin, Gleb; Loktev, Mikhail

doi:10.1364/oe.15.007468

Cited by 17 publications

(9 citation statements)

References 27 publications

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“…The design of these lenses is based on the fact that liquid crystal flows like a liquid but contains molecules that are oriented like a solid. Accordingly, in the nematic phase, they have no specific positional order but line up roughly along a parallel axis which can be manipulated with a magnet or electric field 29,40 . The latest wave of interest in noninvasively adjustable lenses entails using the femtosecond laser or two-photon chemistry to allow for postoperative non-invasive adjustments of refractive error.…”

Section: Five-year Viewmentioning

confidence: 99%

Evaluating the evidence for and against the use of IOLs in infants and young children

Kumar

Lambert

2016

Expert Review of Medical Devices

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Summary Congenital cataracts account for 5–20% of childhood blindness worldwide. In the US, the prevalence of visually significant infantile cataracts is anywhere from 3–4 per 10,000 live births. Infantile cataracts need to be removed early in life in order to prevent the onset of deprivation amblyopia. As a result, cataract surgery is usually performed between age 4–8 weeks depending on the laterality and severity of the cataract. Given advances in the field, pediatric cataract surgery is now a safe and effective intervention for infants, but good visual outcomes require occlusion therapy and optical correction. This review will address current perspectives on the use of intraocular lenses to optically correct infants and young children after cataract surgery, as well as novel designs for intraocular lenses and directions for future research.

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Section: Five-year Viewmentioning

confidence: 99%

Evaluating the evidence for and against the use of IOLs in infants and young children

Kumar

Lambert

2016

Expert Review of Medical Devices

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“…Two principal sets of proposals to solve this problem can be recalled in this aspect. One of them, which can be termed as accommodating lenses, represent varifocal elements based on Alvarez lenses [4][5][6] or programmable lenses based on spatial light modulators (SLMs) [7][8][9]. There were proposed also tunable lenses acting similarly to the eye's crystalline lens [10][11][12] or solutions where the change of the optical power takes place due to the axial displacement of a fixed-focus lens [13], [14].…”

Section: Introductionmentioning

confidence: 99%

Strehl ratios characterizing optical elements designed for presbyopia compensation

et al. 2011

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We present results of numerical analysis of the Strehl ratio characteristics for the light sword optical element (LSOE). For comparison there were analyzed other optical imaging elements proposed for compensation of presbyopia such as the bifocal lens, the trifocal lens, the stenopeic contact lens, and elements with extended depth of focus (EDOF), such as the logarithmic and quartic axicons. The simulations were based on a human eye's model being a simplified version of the Gullstrand model. The results obtained allow to state that the LSOE exhibits much more uniform characteristics of the Strehl ratio comparing with other known hitherto elements and therefore it could be a promising aid to compensate for the insufficient accommodation range of the human eye.

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“…Other possible ways to correct presbyopia include varifocal elements based on the Alvarez lenses 10 or programmable lenses based on spatial light modulators, 11,12 which are classified as accommodative lenses. In addition, adjustable lenses that attempt to mimic how the eye lens functions have been designed, 13,14 and changing the optical power by axial displacement of a lens of a fixed focus has also been implanted and tested.…”

mentioning

confidence: 99%

Compensation of Presbyopia With the Light Sword Lens

Mira-Agudelo

Torres-Sepúlveda

Barrera

et al. 2016

Invest. Ophthalmol. Vis. Sci.

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Citation: Mira-Agudelo A, TorresSepúlveda W, Barrera JF, et al. Compensation of presbyopia with the light sword lens. Invest Ophthalmol Vis Sci. 2016;57:6870-6877. DOI: 10.1167/iovs.16-19409 PURPOSE. We present the first physiological evaluation of the use of the light sword lens (LSL) for presbyopia compensation. The LSL is an axially asymmetric optical element designed for imaging with extended depth of focus. METHODS.A monocular visual simulator setup is implemented to measure visual acuity (VA). Physiological presbyopia is ''mimicked'' in human subjects by paralysis of the ciliary muscle, using topical application of a muscarinic antagonist. The effect of a contact lens-configured LSL on the mimicked presbyopia visual system is evaluated by measuring VA as a function of target vergence. The ability of the LSL to compensate presbyopia for 2 photopic luminance values was also analyzed. RESULTS.The average VA values for 11 subjects suggest that the LSL can compensate for presbyopia across a wide range of target vergences for which the LSL was designed (À3 to 0 D). However, the proposed corrector element causes a loss of distance VA. The mean logMAR VA in that target vergence range was 0.07. The VA curves also show that luminance does not affect the expected behavior of the LSL-corrected presbyopic eye. CONCLUSIONS.These results indicate that the LSL has significant potential as a visual aid for presbyopia.Keywords: aging changes, ophthalmic optics, presbyopia, vision acuity, visual optics P resbyopia is the decrease in accommodative amplitude of the human visual system that occurs with aging of the eye. 1Although presbyopia is a progressive vision disorder that affects everyone after a certain age, 2 there is no effective way to prevent it. Therefore, over the last 2 decades, important optical investigations have been undertaken to find ways to compensate for this visual condition.Over time, different optical methods to correct presbyopia and restore the ability to recognize both distant and near objects have been proposed.3-6 Some proposals include reading glasses, monovision, residual myopia, multifocal lenses used in glasses, contact lenses, and intraocular lenses. Multifocal intraocular lenses usually are bifocal or trifocal. 7,8 Recent proposals include modifying the topography of the cornea with refractive surgery 4 or inserting a small-aperture (pinhole) implant to artificially reduce the size of the pupil and generate a wider depth of focus. 9Other possible ways to correct presbyopia include varifocal elements based on the Alvarez lenses 10 or programmable lenses based on spatial light modulators, 11,12 which are classified as accommodative lenses. In addition, adjustable lenses that attempt to mimic how the eye lens functions have been designed, 13,14 and changing the optical power by axial displacement of a lens of a fixed focus has also been implanted and tested. 15,16 Despite multiple proposals and scientific advances, there is still no entirely satisfactory way to correct presbyopia. For some p...

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Liquid-crystal intraocular adaptive lens with wireless control

Cited by 17 publications

References 27 publications

Evaluating the evidence for and against the use of IOLs in infants and young children

Evaluating the evidence for and against the use of IOLs in infants and young children

Strehl ratios characterizing optical elements designed for presbyopia compensation

Compensation of Presbyopia With the Light Sword Lens

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