Liquid crystal monomers in ventilation and air conditioning dust: Indoor characteristics, sources analysis and toxicity assessment

Jin, Qianqian; Fan, Yinzheng; Lu, Yichun; Zhan, Yuting; Sun, Jiaji; Tao, Danyang; He, Yuhe

doi:10.1016/j.envint.2023.108212

Cited by 16 publications

(4 citation statements)

References 51 publications

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“…In addition, non-combustion sources produce significant amounts of hazardous components such as VOCs from pharmaceuticals and personal care products and toxic products from indoor chemistry [18]. Some emerging contaminates, like liquid crystal monomers, have been detected in various indoor settings [19], leading to concern about their fates and impacts on human health given the ubiquity of technology in electronic products with liquid crystal displays. Solutions for these emerging contaminants differ from the fuel combustion sources, in which mitigation can focus on clean energy transition and improved ventilation.…”

Section: Indoor Air Pollutionmentioning

confidence: 99%

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Updates in Air Pollution: Current Research and Future Challenges

Vilcins,

Christofferson,

Yoon

et al. 2024

Annals of Global Health

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Background:The United Nations has declared that humans have a right to clean air. Despite this, many deaths and disability-adjusted life years are attributed to air pollution exposure each year. We face both challenges to air quality and opportunities to improve, but several areas need to be addressed with urgency.Objective: This paper summarises the recent research presented at the Pacific Basin Consortium for Environment and Health Symposium and focuses on three key areas of air pollution that are important to human health and require more research. Findings and conclusion:Indoor spaces are commonly places of exposure to poor air quality and are difficult to monitor and regulate. Global climate change risks worsening air quality in a bi-directional fashion. The rising use of electric vehicles may offer opportunities to improve air quality, but it also presents new challenges. Government policies and initiatives could lead to improved air and environmental justice. Several populations, such as older people and children, face increased harm from air pollution and should become priority groups for action.

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Section: Indoor Air Pollutionmentioning

confidence: 99%

“…It has been shown that particulate matter from wildfire smoke can trigger asthma attacks in children more than other sources of particulate matter [55]. The new contaminants of concern, liquid crystal monomers, have been shown to be inhaled on fine particles and induce oxidative stress in lung cell models [19,56].…”

Section: Air Pollution and Children's Healthmentioning

confidence: 99%

Updates in Air Pollution: Current Research and Future Challenges

Vilcins,

Christofferson,

Yoon

et al. 2024

Annals of Global Health

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“…Concurrently, a study by Jin et al has shown that exposure to LCMs can cause significant oxidative stress in lung BEAS-2B cells . Notably, LCMs with higher bioconcentration factors and lower molar volumes exert a greater influence on their toxic effects on organisms …”

Section: Introductionmentioning

confidence: 97%

“…Moreover, high-throughput virtual screening and reporter gene assays conducted in a recent study have revealed that the peroxisome proliferator-activated receptor γ (PPARγ) is significantly antagonized by certain LCMs, highlighting their potential as PPARγ antagonists . Concurrently, a study by Jin et al has shown that exposure to LCMs can cause significant oxidative stress in lung BEAS-2B cells . Notably, LCMs with higher bioconcentration factors and lower molar volumes exert a greater influence on their toxic effects on organisms …”

Section: Introductionmentioning

confidence: 99%

Comprehensive Characterization of Organic Light-Emitting Materials in Breast Milk by Target and Suspect Screening

Zheng,

Wang,

Luo

et al. 2024

Environ. Sci. Technol.

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Organic light-emitting materials (OLEMs) are emerging contaminants in the environment and have been detected in various environment samples. However, limited information is available regarding their contamination within the human body. Here, we developed a novel QuEChERS (quick, easy, cheap, effective, rugged, and safe) method coupled with triple quadrupole/high-resolution mass spectrometry to determine OLEMs in breast milk samples, employing both target and suspect screening strategies. Our analysis uncovered the presence of seven out of the 39 targeted OLEMs in breast milk samples, comprising five liquid crystal monomers and two OLEMs commonly used in organic light-emitting diode displays. The cumulative concentrations of the seven OLEMs in each breast milk sample ranged from ND to 1.67 × 103 ng/g lipid weight, with a mean and median concentration of 78.76 and 0.71 ng/g lipid weight, respectively, which were higher compared to that of typical organic pollutants such as polychlorinated biphenyls and polybrominated diphenyl ethers. We calculated the estimated daily intake (EDI) rates of OLEMs for infants aged 0–12 months, and the mean EDI rates during lactation were estimated to range from 30.37 to 54.89 ng/kg bw/day. Employing a suspect screening approach, we additionally identified 66 potential OLEMs, and two of them, cholesteryl hydrogen phthalate and cholesteryl benzoate, were further confirmed using pure reference standards. These two substances belong to cholesteric liquid crystal materials and raise concerns about potential endocrine-disrupting effects, as indicated by in silico predictive models. Overall, our present study established a robust method for the identification of OLEMs in breast milk samples, shedding light on their presence in the human body. These findings indicate human exposure to OLEMs that should be further investigated, including their health risks.

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A method for the determination of 60 liquid crystal monomers in biotic and abiotic samples

Liu,

Li,

et al. 2024

Environmental Chemistry and Ecotoxicology

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Liquid crystal monomers in ventilation and air conditioning dust: Indoor characteristics, sources analysis and toxicity assessment

Cited by 16 publications

References 51 publications

Updates in Air Pollution: Current Research and Future Challenges

Updates in Air Pollution: Current Research and Future Challenges

Comprehensive Characterization of Organic Light-Emitting Materials in Breast Milk by Target and Suspect Screening

A method for the determination of 60 liquid crystal monomers in biotic and abiotic samples

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