Liraglutide-A Novel GLP-1 Analogue

Kalra, Sanjay; Kalra, Bharti; Sharma, Amit

doi:10.2174/187221409789104719

Cited by 7 publications

(7 citation statements)

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“…Effects similar to those seen in the general population may be expected with incretin mimetics in HIV-infected patients. Liraglutide has recently been reported to improve various indices of insulin sensitivity, including HOMA-IR, blood pressure and weight, apart from achieving effective hypoglycemic control [ 43 ]. These properties may make it worthwhile to study the effect of liraglutide and exenatide in HIV-associated diabetes.…”

Section: Strategies To Manage Hyperglycemiamentioning

confidence: 99%

Understanding diabetes in patients with HIV/AIDS

Kalra

Agrawal³

et al. 2011

Diabetol Metab Syndr

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135

145

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Section: Strategies To Manage Hyperglycemiamentioning

confidence: 99%

Understanding diabetes in patients with HIV/AIDS

Kalra

Agrawal³

et al. 2011

Diabetol Metab Syndr

Self Cite

135

145

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“…Incretin mimetics are likely to have similar effects to those seen in the general population, as those in HIV-infected individuals. Liraglutide has been reported to improve various parameters including insulin sensitivity, blood pressure and weight, apart from achieving effective hypoglycaemic control [ 13 ]. Further studies are underway to study the effect of this class of antihyperglycaemics in HIV-associated diabetes.…”

Section: What Is the Treatment Of Diabetes In Hiv Patients? Are Therementioning

confidence: 99%

Human immunodeficiency virus and type 2 diabetes

Avari

Devendra

2017

London Journal of Primary Care

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The prevalence of diabetes is higher amongst individuals infected with HIV. The major contributor to hyperglycaemia is thought to be iatrogenic, with protease inhibitors being most commonly associated to insulin resistance. This article is to update general practitioners on the diagnosis and management of diabetes in HIV-infected patients. Specific considerations are highlighted including interactions of particular diabetic drugs with antiretroviral therapy (ART). We articulate why the use of Hemoglobin A1c (HbA1c) testing is not recommended as a diagnostic tool.

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“…[ 23 ] Liraglutide has recently been reported to improve various indices of insulin sensitivity, including HOMA-IR, blood pressure and weight, apart from achieving effective glycemic control. [ 45 ] These properties may make it worthwhile to study the effect of liraglutide in HIV-associated diabetes.…”

Section: E Vidence /R Ecommendations Formentioning

confidence: 99%

South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome

Kalra

Unnikrishnan

Raza

et al. 2011

Indian J Endocr Metab

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As newer methods of management are made available, and accessible, survival rates with human immunodeficiency virus (HIV) are increasing. This means that chronic, metabolic complications of HIV are becoming more frequent in clinical practice, as acute morbidity is controlled. Management of HIV/acquired immunodeficiency syndrome (AIDS) is gradually expanding to include these chronic and metabolic complications of the disease, and the adverse effects associated with its treatments, including diabetes. Unfortunately, no guidelines are available to help the medical practitioners choose appropriate therapy for patients with these conditions. The aim of the South Asian Consensus Guidelines is to provide evidence-based recommendations to assist healthcare providers in the rational management of type 2 diabetes mellitus in patients with HIV. The development of these guidelines used systematic reviews of available evidence to form its key recommendations. These guidelines and associated review of literature represent a compilation of available knowledge regarding rational management of diabetes in HIV. Patients of diabetes with concomitant HIV infection are managed optimally with insulin therapy and judicious use of highly active antiretroviral therapy with suitable alternatives is also recommended. These guidelines should prove helpful to physicians, not only in South Asia, but also across the globe, while managing patients with coexistent HIV and diabetes.

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Liraglutide-A Novel GLP-1 Analogue

Cited by 7 publications

References 0 publications

Understanding diabetes in patients with HIV/AIDS

Understanding diabetes in patients with HIV/AIDS

Human immunodeficiency virus and type 2 diabetes

South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome

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