Liraglutide limits the immunogenic cell death-mediated ROS propagation and PI3K/AKT inactivation after doxorubicin-induced gonadotoxicity in rats: Involvement of the canonical Hedgehog trajectory

Zaky, Doaa A.; Sayed, Rabab H.; Mohamed, Yasmin S.

doi:10.1016/j.intimp.2023.110212

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…KEGG analysis also revealed that p53 and PI3K-AKT signaling pathways, reportedly involved in ROS-mediated apoptosis, were altered in the WL-808 + laser group. It has been confirmed that p53 activation and PI3K/AKT inactivation can induce cell apoptosis by regulating the downstream mitochondrial apoptotic signaling pathway [ 35 , 36 , 40 ]. Moreover, western blotting analysis further confirmed that compared to the control group, PDT with WL-808 enhanced the expression of p53 and decreased the expression of PI3K and p -AKT in the tendon injury sites.…”

Section: Discussionmentioning

confidence: 99%