Lisinopril-Induced Acute Pancreatitis

Thumma, Soumya; Errico, Kristen; Manchala, Venkata; Mattana, Joseph

doi:10.1097/00045391-900000000-98580

Cited by 3 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hypertriglyceridemia, hypercalcemia, and new medications were ruled out. Lisinopril 14 rarely causes AP. This patient has been on it for years and remained on it without AP recurrence after initial AP attack.…”

Section: Discussionmentioning

confidence: 95%

Cocaine-Induced Acute Pancreatitis

et al. 2020

View full text Add to dashboard Cite

Cocaine use is prevalent worldwide and affects multiple organ systems. Ischemia of the esophagus and small bowel are examples of its gastrointestinal complications. Cocaine-induced pancreatitis is a rare entity. Only 8 cases of cocaine-induced pancreatitis have been described in the literature. We present a rare case of a 61-year-old man cocaine user who presented with his first episode of acute pancreatitis (AP) in which common etiologies of AP were excluded. In addition, we explore the pathophysiology of cocaine-induced AP.

show abstract

Section: Discussionmentioning

confidence: 95%

Cocaine-Induced Acute Pancreatitis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Another rare cause for AP is drug induced and has been estimated to occur with an incidence of 0.1%-2% [ 3 - 4 ]. Although a link between many commonly prescribed drugs and AP has been discussed extensively in the literature, the exact mechanism of injury to the pancreas has not yet been completely elucidated but may be a result of pancreatic duct obstruction secondary to angioedema from increased bradykinins as well as autodigestion from prematurely activated pancreatic enzymes [ 5 ]. Management of drug-induced pancreatitis includes supportive care and immediate withdrawal of the offending medication.…”

Section: Discussionmentioning

confidence: 99%

“…Of the common drugs associated with AP, ACE inhibitors have an even lower incidence of causality [ 5 - 11 ]. They are generally safe and have excellent tolerability with a low risk for adverse effects.…”

Section: Discussionmentioning

confidence: 99%

Another Case of Lisinopril-Induced Acute Pancreatitis

Baum¹,

Walfish²,

Fenster³

et al. 2021

Cureus

View full text Add to dashboard Cite

Lisinopril as a cause for acute drug-induced pancreatitis is an emerging phenomenon that due to its generally low-risk profile often goes unnoticed. The true incidence of drug-induced pancreatitis is unknown, probably because of its nonrecognition among differential diagnosis. Only a handful of lisinopril-induced pancreatitis has been discussed in the literature, and little epidemiological evidence exists to establish true causality. Additionally, many of these reports have been met with skepticism claiming that it is difficult to isolate a true cause since many of these patients had comorbidities or were concomitantly taking other medications that may have contributed to the pancreatitis. Here, we report a case in which a generally otherwise healthy patient presented with acute drug-induced pancreatitis caused by an angiotensin-converting enzyme (ACE) inhibitor taken eight weeks prior to the onset of symptoms. The drug was immediately stopped, and the patient recovered well, with no complications.

show abstract

“…Some of the published reports mentioned acute pancreatitis after lisinopril re-challenge. The proposed mechanism is pancreatic angioedema with pancreatic duct obstruction [23]. A recent population-based study found that, in absence of alcohol, 7 per 10,000 attacks of acute pancreatitis/year are among users of angiotensin-converting enzyme (ACE) inhibitors [23].…”

Section: Antihypertensive Agentsmentioning

confidence: 99%

Updates in drug-induced acute pancreatitis

Alhaddad

Elsabaawy

Elfauomy

et al. 2020

Egypt Liver Journal

View full text Add to dashboard Cite

Background Being infrequent, drug-induced acute pancreatitis (DIP) is an overlooked clinical entity that can be serious with significant morbidity and mortality. Main body A renovative review of drugs incriminated in acute pancreatitis had been presented with all relevant data and case presentations. Antibiotics, antidiabetics, antihypertensive agents, H2 blockers (H2B) and proton pump inhibitors (PPIs), anticancer therapies, and the new direct-acting antiviral therapies (DAAs) of hepatitis C virus (HCV) were discussed pertinently to DIP. Conclusions DIP should be suspected as a potential adverse event to every newly emerged drug. Herein, an updated review of drugs recently alleged to be implicated in DIP.

show abstract

Lisinopril-Induced Acute Pancreatitis

Cited by 3 publications

References 0 publications

Cocaine-Induced Acute Pancreatitis

Cocaine-Induced Acute Pancreatitis

Another Case of Lisinopril-Induced Acute Pancreatitis

Updates in drug-induced acute pancreatitis

Contact Info

Product

Resources

About