“…Pending bacteriologic and virologic laboratory confirmation, an elevated CSF lactic acid is the single key early determinate that should prompt the clinician to begin empiric anti-L. monocytogenes therapy, which is demonstrated by this case. 18,19 The last clinical teaching point is that L. monocytogenes encephalitis may continue for many days before responding to antimicrobial therapy. 3,6,20 The family had given up hope for the patient's recovery early in the course of his illness.…”