Listeriosis: a Rare but Deadly Disease

Donovan, Summer

doi:10.1016/j.clinmicnews.2015.08.001

Cited by 28 publications

(17 citation statements)

References 24 publications

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“…They were first described in 1926 by Murray and colleagues during an outbreak involving rabbits and guinea pigs in a laboratory in Cambridge (Great Britain). At that time, the bacteria were called Bacterium monocytogenes [ 177 , 178 ]. In the early 1980s, this pathogen became associated with human food poisonings [ 179 , 180 ].…”

Section: Listeriosismentioning

confidence: 99%

“…The Listeria genus incorporates 17 bacteria species divided into two groups: Listeria sensu stricto, which includes L. monocytogenes , L. seelgeri, L. ivanovii, L.marthii, L. welshimeri , and L. innocua ; and Listeria sensu lato, which consists of another 11 species divided into three clades, among which there are five new species ( L. aquatic, L. floridensis, L. cornellensis, L. grandensis, and L. riparia ) described by den Bakker et al (2014). Only L. monocytogenes are considered pathogenic for humans [ 177 , 181 , 182 ]. The bacteria are Gram-positive, relatively anaerobic, oxidase-negative, and catalase-positive organisms having the form of small mobile rods (0.4–0.5 × 1–2 μm) that are unable to produce spores [ 177 , 183 ].…”

Section: Listeriosismentioning

confidence: 99%

“…Only L. monocytogenes are considered pathogenic for humans [ 177 , 181 , 182 ]. The bacteria are Gram-positive, relatively anaerobic, oxidase-negative, and catalase-positive organisms having the form of small mobile rods (0.4–0.5 × 1–2 μm) that are unable to produce spores [ 177 , 183 ]. L. monocytogenes are mobile in temperatures ranging between 22 and 30 °C, but at 37 °C they do not form a flagellum [ 183 , 184 ].…”

Section: Listeriosismentioning

confidence: 99%

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Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review

Chlebicz-Wójcik

Śliżewska

2018

IJERPH

374

227

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Zoonoses are diseases transmitted from animals to humans, posing a great threat to the health and life of people all over the world. According to WHO estimations, 600 million cases of diseases caused by contaminated food were noted in 2010, including almost 350 million caused by pathogenic bacteria. Campylobacter, Salmonella, as well as Yersinia enterocolitica and Listeria monocytogenes may dwell in livestock (poultry, cattle, and swine) but are also found in wild animals, pets, fish, and rodents. Animals, often being asymptomatic carriers of pathogens, excrete them with faeces, thus delivering them to the environment. Therefore, pathogens may invade new individuals, as well as reside on vegetables and fruits. Pathogenic bacteria also penetrate food production areas and may remain there in the form of a biofilm covering the surfaces of machines and equipment. A common occurrence of microbes in food products, as well as their improper or careless processing, leads to common poisonings. Symptoms of foodborne infections may be mild, sometimes flu-like, but they also may be accompanied by severe complications, some even fatal. The aim of the paper is to summarize and provide information on campylobacteriosis, salmonellosis, yersiniosis, and listeriosis and the aetiological factors of those diseases, along with the general characteristics of pathogens, virulence factors, and reservoirs.

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Section: Listeriosismentioning

confidence: 99%

Section: Listeriosismentioning

confidence: 99%

Section: Listeriosismentioning

confidence: 99%

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Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review

Chlebicz-Wójcik

Śliżewska

2018

IJERPH

374

227

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“…While the majority of L. monocytogenes isolates are generally susceptible to a large number of antimicrobials, a small portion (Wieczorek et al, 2012;Barbosa et al, 2013;Khen et al, 2015) demonstrate resistance to certain clinically used anti-microbials recommended for treatment of listeriosis infection in pregnancy (Donovan, 2015). Even such low level of resistance is of concern as it may represent an emerging pattern of developing resistance (Khen et al, 2015).…”

Section: Putative Markersmentioning

confidence: 99%

Closing gaps for performing a risk assessment on Listeria monocytogenes in ready‐to‐eat (RTE) foods: activity 3, the comparison of isolates from different compartments along the food chain, and from humans using whole genome sequencing (WGS) analysis

Nielsen

Björkman

Kiil

et al. 2017

EFSA Supporting Publications

111

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This report presents the results of the project "Closing gaps for performing a risk assessment on Listeria monocytogenes in ready-to-eat (RTE) foods: activity 3, the comparison of isolates from different compartments along the food chain, and from humans using whole genome sequencing (WGS) analysis". The main objective was to compare L. monocytogenes isolates collected in the EU from ready-to-eat (RTE) foods, compartments along the food chain and from human cases by the use of WGS. A total of 1,143 L. monocytogenes isolates were selected for the study, including 333 human clinical isolates and 810 isolates from the food chain. The isolates were whole genome sequenced. The phylogeny showed a clear delineation between L. monocytogenes lineages and between clonal complexes within lineages. A range of typing methods were applied to the sequence data, providing the framework to answer questions on genetic diversity and epidemiological relationships. Retrospective analysis of nine outbreaks showed that WGS is a powerful tool in national and international outbreak investigations as WGS can accurately rule isolates in or out of outbreaks. Source attribution models showed bovine reservoir to be the main source of human disease although other sources also contributed and generally confidence intervals were high. Numerous consistent genetic linkages between a priori unlinked strains were identified, some of which involved isolates from multiple countries. The presence of putative markers conferring the potential to survive/multiply in the food chain and/or cause disease in humans was explored by detecting the presence of putative virulence genes, AMR genes and factors conferring the ability to persist in the food processing chain. This study has demonstrated one of the major benefits of WGS, which is the ability to address a wide range of questions including those on virulence, antimicrobial resistance, source attribution, surveillance and outbreak detection and investigation, in a single experiment.

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“…L. monocytogenes is one of the major food pathogens leading to severe invasive illness called listeriosis. Listeriosis carries a high hospitalization and mortality rate (Donovan, ). In 94% of confirmed cases, there is a need for hospitalization, and approximately 16% of patients die (Scallan et al., ).…”

Section: Listeria Monocytogenesmentioning

confidence: 99%

Food Safety Interventions to Control Listeria monocytogenes in the Fresh Apple Packing Industry: A Review

Pietrysiak

Smith

Ganjyal

2019

Comp Rev Food Sci Food Safe

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Listeria monocytogenes, in fresh and ready‐to‐eat produce such as whole fresh apples, is of concern as there is no “kill step” in their packing process that would eliminate the pathogenic bacteria. Recent listeriosis outbreaks revealed that insufficient cleaning and sanitation practices in fresh apple packing houses may lead to contamination of fruit with L. monocytogenes. This article discusses three fundamental aspects for ensuring microbiological safety of fresh apples: protection of fresh apples from microbial contamination during the packing process, decontamination intervention techniques, and the challenges in removal of L. monocytogenes from fresh apples. Currently used and novel methods of fresh produce decontamination are discussed and evaluated on their usefulness for the apple packing process. Additionally, present regulatory requirements, possible routes of produce contamination, and bacteria attachment and survival mechanisms are described. Optimum methods for microbial decontamination of whole fresh apples are still to be determined. Critical aspects that should be considered in developing the interventions include apple morphology, conditions and scale of the packing process, and influence of the interventions on apple quality. Evaluation of the currently used and emerging decontamination methods indicated that the hurdle technology and rotating use of sanitizers to avoid development of bacterial biofilm resistance may give the best results, although not conclusively.

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Listeriosis: a Rare but Deadly Disease

Cited by 28 publications

References 24 publications

Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review

Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review

Closing gaps for performing a risk assessment on Listeria monocytogenes in ready‐to‐eat (RTE) foods: activity 3, the comparison of isolates from different compartments along the food chain, and from humans using whole genome sequencing (WGS) analysis

Food Safety Interventions to Control Listeria monocytogenes in the Fresh Apple Packing Industry: A Review

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