Litchi chinensis: medicinal uses, phytochemistry, and pharmacology

Ibrahim, Sabrin R. M.; Mohamed, Gamal A.

doi:10.1016/j.jep.2015.08.054

Cited by 115 publications

(68 citation statements)

References 80 publications

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“…Component analysis and structure identification. Both literatures and our research proved that the pericarp of litchi contains great amount of polyphenols (Ibrahim and Mohamed, 2015;Sun et al, 2010;Li et al, 2015). Therefore, we first contrasted the content of total phenols in CLPE and PLPE by Folin-Ciocalteau method.…”

Section: Methodssupporting

confidence: 69%

“…In Taiwan and Vietnam, the fruit is an excellent thirst quencher and used as a tonic for brain, heart and liver (Ibrahim and Mohamed, ). It has proved that the pericarp of litchi contains great amount of polyphenols with good antioxidant activity (Ibrahim and Mohamed, ; Sun et al , ; Duan et al , ). Considering its traditional use for chest tightness or chest pain, we speculated that the extract of litchi pericarp might exert a protective effect on cardiovascular system.…”

Section: Introductionmentioning

confidence: 99%

“…The main component of litchi pericarp is procyanidine which belongs to the -3-alcohol polyphenols and has many pharmacological activities, such as antioxidation, cardiovascular protection and so on. Procyanidin A2 and (À)-epicatechin were identified in the litchi pericarp, but there is still a lack of comprehensive quality control standards (Ibrahim and Mohamed, 2015;Sun, 2010). In the preliminary study, we carried the response surface optimization test and got the crude extract of litchi pericarp; the yield of original anthocyanin was used as the indicator to optimize the production process (Li et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Anti‐myocardial Ischemia Effect and Components of Litchi Pericarp Extracts

Chen

Zhang

et al. 2017

Phytotherapy Research

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Litchi (Litchi chinensis Sonn.) is a famous fruit in south China, and it is also effective for chest tightness or chest pain, irritability, flatulence, epigastric pain and neuralgic pain, hernia pain and testicular swelling, cough, etc. It is valued because a great amount of polyphenol was found in litchi pericarp. In this paper, we got litchi pericarp pure extract by a simple purification method, then evaluated its activity to clear oxygen free radicals in vitro, and evaluated its myocardial protection effect in vivo through acute myocardial ischemia rat model. The results showed that the pure extract had protective effect on myocardial ischemia injury in a certain dose-effect relationship, which reflected in the electrocardiogram, myocardial pathological morphology and other indicators such as cardiac function enzymes, serum and myocardial antioxidant capacity, and eNOS, Bcl-2 and Bax gene expression. Furthermore, we analyzed the components of pure extract by UPLC-MS, ESI-MS and NMR. The main components of PLPE were procyanidin which were identified as procyanidin B2(1), (-)-epicatechin(2), epicatechin-(4β → 8,2β → O → 7)-epicatechin-(4β → 8)-epicatechin(3), A-type procyanidin trimer(4), B-type procyanidin dimer(5) and procyanidin A2(6).This study proved that litchi pericarp extract may have antioxidant activity and cardioprotection effect. It suggested that litchi pericarp may be good for cardiovascular disease. Copyright © 2017 John Wiley & Sons, Ltd.

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Section: Methodssupporting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Anti‐myocardial Ischemia Effect and Components of Litchi Pericarp Extracts

Chen

Zhang

et al. 2017

Phytotherapy Research

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“…Pharmacognostic study and phytochemical screening of different fruit parts has revealed them to be a treasure box of several biologically active molecules. They are reported to possess anti-inflammatory, antiallergic, anti-flatulent, anti-diabetic, anti-hyperlipidemic, anti-platelet, anti-pyretic, anti-obesity, cardio-protective, anti-viral and anti-cancer effects (Kilari and Putta, 2016;Ibrahim and Mohamed, 2015;Islam et al, 2013;Patel et al, 2012;Zhao et al, 2007). They have been traditionally used to treat gastralgia, neuralgia, cough, hernia-like conditions, blood stasis in women and testicular swelling (Hsu et al, 2012).…”

Section: Description Of Fruits and Spectrum Of Pharmacological Activimentioning

confidence: 99%

Polyphenols derived from four indigenous Indian fruits for cancer chemoprevention and chemotherapy

Sutapa¹,

Vansh²,

Agarwal³

et al. 2016

J. Med. Plants Res.

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Cancer is one of the major causes of death worldwide, including developing and underdeveloped nations. Mortality and morbidity data suggest that incidences are higher than those of the cardiovascular diseases. High cost and occurrence of numerous side and adverse effects associated with conventional anticancer regimes has necessitated shifting the focus towards the practice of traditional alternative and complementary medicine. Emerging evidence on the beneficial link of dietary components with lower cancer occurrence has been instrumental in determining the course of cancerrelated studies. Consumption of fruits rich in polyphenols has proven to inhibit the process of carcinogenesis and tumor growth, with positive outcomes in terms of survival and quality of life of the patient and thus should be encouraged to combat cancer. The objective of the present review is to highlight the underlying mechanisms of apoptosis induced by the different polyphenolic constituents in four Indian fruits, namely litchi, Indian gooseberry, Indian blackberry and Ziziphus jujube. However, it must be kept in mind that benefits of consuming fruits rich in polyphenols should not be over-judged through food fortification or supplementation with these active principles. Conclusive evidence of the beneficial effects is yet to come through future studies in humans since most of the data have been obtained from in vitro studies.

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“…Apart from being consumed fresh, litchi fruit is also processed into juice, canned litchi, and is dried. Litchi juice typically contains sugar, widely appreciated flavor,minerals, vitamins, and various phenolics, and whichcan compete in the juice market; recently litchi juice, fermented by Lactobacillus, which increases its health benefits with probiotics has emerged on the market (Ibrahim & Mohamed, 2015). However, non-enzymatic browning is the major cause of quality deterioration during storage of probiotic litchi juice.…”

Section: Introductionmentioning

confidence: 99%

Changes in Quality Attributes Related to Browning during Storage of Litchi Juice Fermented by Lactobacillus

Yuan¹,

Yu²,

Xu³

et al. 2019

JFR

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Litchi juice fermented by Lactobacillus casei was heated (95°C, 1 min) and stored in a dark place at 25°C. Changes in quality attributes (color, 5-hydroxymethylfurfural (5-HMF) phenolic compounds, antioxidant capacity, sugars, free amino acids, and others) related to browning in fermented litchi juice were investigated during the six months of storage. Noticeable visual changes due to browning were observed during storage of fermented litchi juice, especially in the upper part of the juice bottle, and the value of color difference (△E) increased to 7.12±0.04 after six months of storage. The 5-HMF content increased with the increase in storage time, which rose from 0 to 2.31±0.16 mg/L after six months of storage. Five soluble phenolic compounds (rutin, narcissoside, quercetin, kaempferol-rutinose-rhamnoside, and isorhamnetin-rutinose-rhamnoside) were identified in fermented litchi juice, none of which showed a significant decrease (P>0.05), whereas a tendency for total phenolic content to decrease was observed during storage of fermented litchi juice. Adding 0.3 g/L of sodium sulfite can inhibit the browning reaction in fermented litchi juice and decrease the formation of 5-HMF as well as the loss of total phenolics.

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Litchi chinensis: medicinal uses, phytochemistry, and pharmacology

Cited by 115 publications

References 80 publications

Anti‐myocardial Ischemia Effect and Components of Litchi Pericarp Extracts

Anti‐myocardial Ischemia Effect and Components of Litchi Pericarp Extracts

Polyphenols derived from four indigenous Indian fruits for cancer chemoprevention and chemotherapy

Changes in Quality Attributes Related to Browning during Storage of Litchi Juice Fermented by Lactobacillus

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