Literature review. Noninvasive fungal rhinosinusitis

Cojocari, Lucia; Sandul, Alexandru

doi:10.1515/rjr-2017-0008

Cited by 6 publications

(5 citation statements)

References 37 publications

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“…T2weighted images may show signal void areas due to calcifications and paramagnetic metals such as iron, magnesium and manganese deposited within the mycetoma. No tissue invasion is noted [38].…”

Section: Imaging Featuresmentioning

confidence: 97%

“…The pathogenesis of FB has been attributed to three possible etiologies, i.e., airborne route, odontogenic cause and mixed etiology [38].…”

Section: Fungal Ball (Fb) [Aka Sinus Mycetoma/ Aspergilloma]mentioning

confidence: 99%

“…Nasal endoscopic examination is nonconclusive in most cases. However, sinus endoscopy, in case of maxillary fungal ball can highlight the characteristic appearance of ''fungus ball'' and allow harvesting of material for culture and histopathological analyses [38].…”

Section: Clinical Presentationmentioning

confidence: 99%

“…In imaging studies, fungus ball appears as a rounded or ovoid mass within the lumen of a paranasal sinus presenting typically with single sinus involvement [42]. Nonenhanced CT is the imaging modality of choice with high specificity [38]. It also allows for assessment of any calcifications [14].…”

Section: Imaging Featuresmentioning

confidence: 99%

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Fungal Rhinosinusitis: Unravelling the Disease Spectrum

Singh

2019

J. Maxillofac. Oral Surg.

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Fungal rhinosinusitis (FRS), once considered a rare disease, has seen a steep rise in incidence in recent times. This global rise in the burden of fungal disease is a consequence of an increment in the population with weakened immune systems. Increased life expectancy with rise in conditions like diabetes mellitus, medical advancements with invasive interventions, use of immunosuppressive drugs and chemo-radiotherapy all lead to unique risk situations. The situation becomes more alarming with the fact that there has been a significant rise in cases in immune-competent hosts with no predisposing factors. FRS represents a wide spectrum of disease ranging from the mild form of superficial colonization, allergic manifestations to life threatening extensive invasive disease. The categorization of disease into acute and chronic and invasive or noninvasive is important factor with implications in disease management and prognosis and this has been emphasized greatly in recent years. Diagnosis of FRS has been a challenge as the presenting clinical signs and symptoms and radiographic manifestations are often nonspecific. Definitive diagnosis requires direct fungi identification and hence culture and microscopic examination remain the gold standard. Availability of advanced and rapid diagnostic techniques is rare in majority of developing nations. Therapeutic dilemmas are another aspect of the management of FRS as in spite of the availability of new antifungal drugs, treatment is often empirical due to non-availability of early diagnosis, rapid disease progression and high costs of antifungal drugs. A description of the different types of FRS, their diagnosis and management has been presented in this review.

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Section: Imaging Featuresmentioning

confidence: 97%

“…The pathogenesis of FB has been attributed to three possible etiologies, i.e., airborne route, odontogenic cause and mixed etiology [38].…”

Section: Fungal Ball (Fb) [Aka Sinus Mycetoma/ Aspergilloma]mentioning

confidence: 99%

Section: Clinical Presentationmentioning

confidence: 99%

Section: Imaging Featuresmentioning

confidence: 99%

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Fungal Rhinosinusitis: Unravelling the Disease Spectrum

Singh

2019

J. Maxillofac. Oral Surg.

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“…Critically invasive, inveterately invasive, and granulomatous are the three forms of intrusive FRS [3]. Fungi-linked eosinophilic rhinosinusitis comprising adverse FRS and fungal ball are two noninvasive types of FRS [4-5].…”

Section: Introductionmentioning

confidence: 99%

Frequency of Granulomatous Invasive Fungal Sinusitis in Patients with Clinical Suspicion of Chronic Fungal Rhinosinusitis

Sharif¹,

Ali²,

Nisar³

2019

Cureus

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Introduction One of the common causes of chronic sinusitis is a fungal infection, and there are various types of fungal rhinosinusitis (FRS). Missed diagnosis of occasional granulomatous invasion of fungal sinusitis can lead to involvement in the central nervous system. The aim of this study is to determine the frequency of granulomatous invasive fungal sinusitis (GIFS) in patients with clinical suspicion of chronic FRS. Methods We conducted a descriptive cross-sectional study in the Department of Ear, Nose and Throat (ENT), Nishtar Hospital, Multan from January 1, 2017 to July 1, 2018. Eighty-one patients with chronic FRS participated in the study. After informed consent, nasal tissue was biopsied for granulomatous fungal invasion. Results The frequency of GIFS was 29.6% (n=24) in this study. The significant risk factors included duration of chronic FRS for more than 12 weeks, history of diabetes mellitus, and living status as rural. Conclusion GIFS is a common complication in patients with clinical suspicion of chronic FRS. Nasal biopsy should be a common practice among patients of chronic FRS who have a long duration of disease and a history of diabetes mellitus.

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