Lithiase biliaire du nourrisson, de l’enfant et de l’adolescent

Debray, Dominique; Franchi‐Abella, Stéphanie; Irtan, Sabine; Girard, M

doi:10.1016/j.lpm.2011.09.018

Cited by 15 publications

(7 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Possible reasons suggested include haemolytic disease, infectious aetiologies, metabolic causes, obesity, familial risks, dietary and environmental factors and medications; however, most of the cases are still idiopathic in several series 27,28 . Several early series had reported the higher proportion of pigment gall stones thereby strengthening the relation between haemolytic disease and gallstones 26,29 . Recent evidence also shows that an increased incidence of childhood obesity often parallels an increased incidence of childhood gallstone disease 28,30 .…”

Section: Meanmentioning

confidence: 97%

Paediatric cholelithiasis: our experience at a tertiary care centre

Thakur

Hasan

Rahul

et al. 2021

Sri Lanka J Child Health

View full text Add to dashboard Cite

Background: With increased incidence of symptomatic and asymptomatic gallstones in children, paediatric cholelithiasis has emerged as an important pathology in children. A retrospective study evaluates paediatric cholelithiasis and its management at a tertiary centre. Objectives:To study the spectrum of paediatric cholelithiasis and its management issues.Method: A retrospective study was conducted at a tertiary care on all patients of paediatric cholelithiasis (children less than 14 years) who were managed from April, 2017 to March, 2020. Data regarding demographic profile, clinical history, investigation results, management and postoperative outcomes were collected and analysed.Results: Of the 52 ultrasound-confirmed cases of gallstones, 35 showed biliary and dyspeptic symptoms; while 17 were asymptomatic. Males outnumbered females; no child less than three years came with gallstones. No definite aetiology was found in 32 cases. Cholecystectomy was done in 40 patients (laparoscopic in 37 cases, open in three cases). Stone analysis revealed mixed stones (thirty cases), pigment stones (eight cases) and pure cholesterol stones (two cases). 10/17 cases of asymptomatic gallstones showed complete stone resolution from gallbladder on follow-up sonogram after six months; 5/17 showed no regression of stones (one symptomatic and rest four underwent elective surgery due to parental anxiety); 2/17 cases were lost to follow up. No major complication was seen.

show abstract

Section: Meanmentioning

confidence: 97%

Paediatric cholelithiasis: our experience at a tertiary care centre

Thakur

Hasan

Rahul

et al. 2021

Sri Lanka J Child Health

View full text Add to dashboard Cite

show abstract

“…2 In the general population, choledocholithiasis occurs in 10%-20% of children with gallstones. 1 In patients with SCD, the incidence of choledocholithiasis is estimated to be around 18%. 3 Postcholecystectomy complications are multiple, and late complications include papillary stenosis, retained or recurrent common bile duct stones, incomplete resection of the gallbladder, and biliary stricture.…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of cholelithiasis in children with SCD is estimated to be 10%–37% 2 . In the general population, choledocholithiasis occurs in 10%–20% of children with gallstones 1 . In patients with SCD, the incidence of choledocholithiasis is estimated to be around 18% 3 …”

Section: Introductionmentioning

confidence: 99%

Gallbladder remnant: A potential source for biliary stones postcholecystectomy; a case report in a child with sickle cell disease

Miri,

Abdessalam,

Powers

et al. 2024

JPGN rep.

View full text Add to dashboard Cite

Stone formation in a gallbladder remnant is a rare postcholecystectomy complication. This report describes the case of gallstones in a gallbladder remnant of an adolescent with sickle cell disease (SCD) years after laparoscopic cholecystectomy. A 15‐year‐old female with SCD presented to our gastroenterology clinic with concerns of recurrent choledocholithiasis despite cholecystectomy 2 years before presentation. About 4 months before presentation to our clinic, she was evaluated at the referring physician's emergency department for recurrent severe abdominal pain of 1 month duration. After admission to the hospital, common bile duct stones were seen on magnetic resonance cholangiopancreatography (MCRP) imaging and subsequently removed via endoscopic retrograde cholangiopancreatography (ERCP). On review of her MRCP and ERCP at our hospital, a remnant of gallbladder containing multiple stones was identified. She subsequently underwent a laparoscopic resection of the gallbladder remnant. Clinicians should consider biliary duct imaging in children with biliary colic following cholecystectomy, especially those with history of chronic hemolysis.

show abstract

“…It was found that copper is associated with taurochenodexoxycholate and might be responsible for the elevated tissue copper levels of gallbladder in WD. Moreover, acute gallbladder hydrops or cholecystolithiasis have been also described in WD and have been assumed to be causative for an unbalanced Cu metabolism [12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Copper and Trace Elements in Gallbladder form Patients with Wilson’s Disease Imaged and Determined by Synchrotron X-ray Fluorescence

2021

View full text Add to dashboard Cite

Investigations about suspected tissue alterations and the role of gallbladder in Wilson’s disease (WD)—an inherited genetic disease with impaired copper metabolism—are rare. Therefore, tissue from patients with genetically characterised WD was investigated by microscopic synchrotron X-ray fluorescence (µSRXRF). For two-dimensional imaging and quantification of elements, X-ray spectra were peak-fitted, and the net peak intensities were normalised to the intensity of the incoming monochromatic beam intensity. Concentrations were calculated by fundamental parameter-based program quant and external standardisation. Copper (Cu), zinc (Zn) and iron (Fe) along with sulphur (S) and phosphorus (P) mappings could be demonstrated in a near histological resolution. All these elements were increased compared to gallbladder tissue from controls. Cu and Zn and Fe in WD-GB were mostly found to be enhanced in the epithelium. We documented a significant linear relationship with Cu, Zn and sulphur. Concentrations of Cu/Zn were roughly 1:1 while S/Cu was about 100:1, depending on the selected areas for investigation. The significant linear relationship with Cu, Zn and sulphur let us assume that metallothioneins, which are sulphur-rich proteins, are increased too. Our data let us suggest that the WD gallbladder is the first in the gastrointestinal tract to reabsorb metals to prevent oxidative damage caused by metal toxicity.

show abstract

Lithiase biliaire du nourrisson, de l’enfant et de l’adolescent

Cited by 15 publications

References 24 publications

Paediatric cholelithiasis: our experience at a tertiary care centre

Paediatric cholelithiasis: our experience at a tertiary care centre

Gallbladder remnant: A potential source for biliary stones postcholecystectomy; a case report in a child with sickle cell disease

Copper and Trace Elements in Gallbladder form Patients with Wilson’s Disease Imaged and Determined by Synchrotron X-ray Fluorescence

Contact Info

Product

Resources

About