Lithium Carbonate Intoxication

Simard, Marie

doi:10.1001/archinte.1989.00390010054004

Cited by 81 publications

(3 citation statements)

References 21 publications

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“…Concerns are not limited to exposure during the first trimester. Third-trimester exposure to Li late in pregnancy, or neonatal exposure through breastfeeding, has also caused adverse effects, specifically a neonatal adaptation syndrome, described in early case studies as “floppy baby syndrome” that includes lethargy, hypotonicity and cyanosis [222], and more recently has been observed to also involve symptoms such as muscle twitching, respiratory problems, feeding difficulties, cardiac arrhythmias, and poor reflexes [223,224,225]. One study also found that lithium-exposed infants had significantly higher birth weights [219].…”

Section: Effects Of Maternal Pharmacotherapy On Fetal Neonatal Amentioning

confidence: 99%

Use of Prescribed Psychotropics during Pregnancy: A Systematic Review of Pregnancy, Neonatal, and Childhood Outcomes

Creeley

Denton

2019

Brain Sciences

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This paper reviews the findings from preclinical animal and human clinical research investigating maternal/fetal, neonatal, and child neurodevelopmental outcomes following prenatal exposure to psychotropic drugs. Evidence for the risks associated with prenatal exposure was examined, including teratogenicity, neurodevelopmental effects, neonatal toxicity, and long-term neurobehavioral consequences (i.e., behavioral teratogenicity). We conducted a comprehensive review of the recent results and conclusions of original research and reviews, respectively, which have investigated the short- and long-term impact of drugs commonly prescribed to pregnant women for psychological disorders, including mood, anxiety, and sleep disorders. Because mental illness in the mother is not a benign event, and may itself pose significant risks to both mother and child, simply discontinuing or avoiding medication use during pregnancy may not be possible. Therefore, prenatal exposure to psychotropic drugs is a major public health concern. Decisions regarding drug choice, dose, and duration should be made carefully, by balancing severity, chronicity, and co-morbidity of the mental illness, disorder, or condition against the potential risk for adverse outcomes due to drug exposure. Globally, maternal mental health problems are considered as a major public health challenge, which requires a stronger focus on mental health services that will benefit both mother and child. More preclinical and clinical research is needed in order to make well-informed decisions, understanding the risks associated with the use of psychotropic medications during pregnancy.

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Section: Effects Of Maternal Pharmacotherapy On Fetal Neonatal Amentioning

confidence: 99%

Use of Prescribed Psychotropics during Pregnancy: A Systematic Review of Pregnancy, Neonatal, and Childhood Outcomes

Creeley

Denton

2019

Brain Sciences

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“…A number of pharmacological agents can lead to nephrogenic diabetes insipidus, and these include lithium, demethylchlortetracycline, methoxyflurane and certain hypoglycemia agents, such as glyburide [84]. Hypercalcemia can lead to nephrogenic diabetes insipidus [85], as can a number of renal interstitial disorders [83] and chronic lithium administration [86].…”

Section: Diabetes Insipidusmentioning

confidence: 99%

Salt and Water Homeostasis

Arieff¹

1999

Frontiers of Hormone Research

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“…La dialyse peritoneale semble plus efficace que la diurese forcee(57). Dans le cas d'intoxicationgrave ou la lithemie est superieure a3,5 mmol/L, ou que la condition du patient est instable quelle que soit la lithemie, l'hemodialyse demeure le traitement de choix(50). Ala lumiere des travaux de Swartz et Jones(48), cette derniere recommandation peut etre contestee.…”

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