Lithium-Induced Neurotoxicity: A Case Study

Abstract

BACKGROUND In patients presenting with neurological deficits, identifying the cause can be challenging. METHODS This case study discusses a condition that is not commonly seen. DISCUSSION Although lithium toxicity syndrome is not as familiar as other causes of neurological issues, this should be considered for any patient who presents with unexplained neurological deficits and a history of taking this medication. CONCLUSION If toxicity is not recognized early, the patient can be left with irreversible neurological symptoms, also known as syndrome of irreversible lithium-effectuated neurotoxicity, which impacts quality of life or can even cause death.

A case of unsuspected chronic lithium toxicity presenting with neurological symptoms

“…Neurological symptoms may consider irreversible if they persists for more than two months in the form of persistent cerebellar dysfunction, persistent extrapyramidal syndrome, persistent brainstem dysfunction, dementia, choreo athetoid movements, peripheral neuropathy (both motor and sensory), myopathy, optic neuritis etc. 2,5 .…”