Lithium: The defining element?

Mood disorders: neurocognitive models

“…Overall results from meta‐analyses indicate that increased ACC activity is associated with better treatment response, increased insula and striatum activation with a poorer treatment response, and differences in connections between the limbic‐cortical and cortical‐cortical pathways were able to distinguish between individuals responsive to CBT and medication . This area of research is important because identifying potential markers of treatment response will allow us to improve treatment outcomes for mood disorders as well as predict whether certain individuals are likely to require additional treatment, therefore tailoring treatment to the needs of the individual .…”