Live long and prosper: “<scp>G</scp>ermline stem cell maintenance revisited” (retrospective on DOI: 10.1002/bies.201000085)

Extavour, Cassandra G.

doi:10.1002/bies.201300067

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…While all of these studies document an outcome of environmental variation on sperm quantity and quality, none examined the mechanisms by which the increase in sperm numbers occurred. Ultimately, sperm availability depends on the germline, cells set aside for the production of gametes (Extavour, 2013;Moore, 2014). Males have the potential, through germline stem cells, to modulate sperm production (Kaczmarczyk & Kopp, 2011;Moore, 2014;Ramm & Schärer, 2014).…”

Section: Introductionmentioning

confidence: 99%

A study of the transit amplification divisions during spermatogenesis in Oncopetus fasciatus to assess plasticity in sperm numbers or sperm viability under different diets

Duxbury

Weathersby

Sanchez

et al. 2018

Ecology and Evolution

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Oncopeltus fasciatus males fed the ancestral diet of milkweed seeds prioritize reproduction over lifespan as evidenced by higher rates of fertility and shorter lifespans than males from the same population fed the adapted diet of sunflower seeds. We examined the proximate mechanisms by which milkweed‐fed males maintained late‐life fertility. We tested the hypothesis that older milkweed‐fed males maintained fertility by producing more, higher quality sperm. Our results, that older males have more sperm, but their sperm do not have higher viability, are in general agreement with other recent studies on how nutrition affects male fertility in insects. We further examined the mechanisms by which sperm are produced by examining the progression of spermatogonial cells through the cell cycle during the transit amplification divisions. We demonstrated that diet affects the likelihood of a spermatocyst being in the S‐phase or M‐phase of the cell cycle. Given work in model systems, these results have implications for subtle effects on sperm quality either through replication stress or epigenetic markers. Thus, viability may not be the best marker for sperm quality and more work is called for on the mechanisms by which the germline and the production of sperm mediate the cost of reproduction.

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Section: Introductionmentioning

confidence: 99%

A study of the transit amplification divisions during spermatogenesis in Oncopetus fasciatus to assess plasticity in sperm numbers or sperm viability under different diets

Duxbury

Weathersby

Sanchez

et al. 2018

Ecology and Evolution

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The trade‐off between investment in weapons and fertility is mediated through spermatogenesis in the leaf‐footed cactus bug Narnia femorata

Cavender

Ricker

Lyon

et al. 2021

Ecology and Evolution

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Males have the ability to compete for fertilizations through both precopulatory and postcopulatory intrasexual competition. Precopulatory competition has selected for large weapons and other adaptations to maximize access to females and mating opportunities, while postcopulatory competition has resulted in ejaculate adaptations to maximize fertilization success. Negative associations between these strategies support the hypothesis that there is a trade‐off between success at pre‐ and postcopulatory mating success. Recently, this trade‐off has been demonstrated with experimental manipulation. Males of the leaf‐footed cactus bug Narnia femorata use hind limbs as the primary weapon in male–male competition. However, males can drop a hind limb to avoid entrapment. When this autotomy occurs during development, they invest instead in large testes. While evolutionary outcomes of the trade‐offs between pre‐ and postcopulatory strategies have been identified, less work has been done to identify proximate mechanisms by which the trade‐off might occur, perhaps because the systems in which the trade‐offs have been investigated are not ones that have the molecular tools required for exploring mechanism. Here, we applied knowledge from a related model species for which we have developmental knowledge and molecular tools, the milkweed bug Oncopeltus fasciatus , to investigate the proximate mechanism by which autotomized N . femorata males developed larger testes. Autotomized males had evidence of a higher rate of transit amplification divisions in the spermatogonia, which would result more spermatocytes and thus in greater sperm numbers. Identification of mechanisms underlying a trade‐off can help our understanding of the direction and constraints on evolutionary trajectories and thus the evolutionary potential under multiple forms of selection.

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Live long and prosper: “Germline stem cell maintenance revisited” (retrospective on DOI: 10.1002/bies.201000085)

Cited by 2 publications

References 6 publications

A study of the transit amplification divisions during spermatogenesis in Oncopetus fasciatus to assess plasticity in sperm numbers or sperm viability under different diets

A study of the transit amplification divisions during spermatogenesis in Oncopetus fasciatus to assess plasticity in sperm numbers or sperm viability under different diets

The trade‐off between investment in weapons and fertility is mediated through spermatogenesis in the leaf‐footed cactus bug Narnia femorata

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