Child labor migration is a critical issue that has received limited attention from academic and policy domains in many developing countries. This article analysis the causes of child labor migration and working conditions at the destination of temporary inter-rural child labor migration from Sekela district, Northwest Ethiopia. Mixed research methods is employed. Quantitative data is collected from randomly selected 204 respondents engaged in child labor migration. Focus group discussion, informal conversational interviews, and observation are also undertaken to gather qualitative data. Most child labor migrants participate in child labor migration due to localized economic constraints, which are reflected through a desire to have modern goods and cloth, food scarcity, and resource degradation. Also, the expansion of commercial farms at destination areas directly or indirectly due to the globalized market indicates that migrant children’s local labor cannot be delinked from material realities created by both national and international economic policy. The income from child labor migration supports children and their households’ livelihood, though it is at the expense of children’s education as well as exposure to worse working conditions at their destination in terms of exploitation, underpayment, malnutrition, breaching of an agreement by employers, and harassment. Hence, to exploit the benefits and minimize the risks, balanced measures should be taken at the origin and destination. Education programs should be supportive in increasing food productivity and assisting households to diversify their means of income by allowing them to participate in non-farm activities. It is also essential to the establishment of support groups in migrant destination places and the expansion of labor inspectorates who continuously supervise the safety of child labor migrants.