Abstract:Total parenteral nutrition (TPN) is a life-saving nutritional therapy in conditions where enteral nutrition is contraindicated or inadequate. However, it has been associated with side effects, one of which is parenteral nutrition–associated liver damage (PNALD). The main features of PNALD are cholestasis, fatty liver disease, and early fibrosis, followed by disease progression, cirrhosis, and liver failure. Risk factors for parenterally fed patients include short bowel syndrome, bacterial overgrowth and transl… Show more
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